Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4
…, W Jalabi, KB Shpargel, KT Farabaugh… - Journal of …, 2012 - Soc Neuroscience
Intraperitoneal injection of the Gram-negative bacterial endotoxin lipopolysaccharide (LPS)
elicits a rapid innate immune response. While this systemic inflammatory response can be …
elicits a rapid innate immune response. While this systemic inflammatory response can be …
A tale of two proteins: PACT and PKR and their roles in inflammation
E Chukwurah, KT Farabaugh, BJ Guan… - The FEBS …, 2021 - Wiley Online Library
Inflammation is a pathological hallmark associated with bacterial and viral infections, autoimmune
diseases, genetic disorders, obesity and diabetes, as well as environmental stresses …
diseases, genetic disorders, obesity and diabetes, as well as environmental stresses …
PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation
The inability of cells to adapt to increased environmental tonicity can lead to inflammatory
gene expression and pathogenesis. The Rel family of transcription factors TonEBP and NF-κB …
gene expression and pathogenesis. The Rel family of transcription factors TonEBP and NF-κB …
[HTML][HTML] Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator–activated receptor γ (PPARγ) …
The breakdown of stored fat deposits into its components is a highly regulated process that
maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated …
maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated …
Protein kinase R mediates the inflammatory response induced by hyperosmotic stress
KT Farabaugh, M Majumder, BJ Guan… - … and Cellular Biology, 2017 - Taylor & Francis
High extracellular osmolarity results in a switch from an adaptive to an inflammatory gene
expression program. We show that hyperosmotic stress activates the protein kinase R (PKR) …
expression program. We show that hyperosmotic stress activates the protein kinase R (PKR) …
[HTML][HTML] The “Levine effect” and the father of modern diabetes research
KT Farabaugh - Journal of Biological Chemistry, 2021 - ASBMB
Even just over a century ago, a diagnosis of diabetes was practically a death sentence.
There was no treatment but to attempt to extend the survival of those afflicted via a so-called ‘…
There was no treatment but to attempt to extend the survival of those afflicted via a so-called ‘…
Insights into a Novel Signaling Pathway that Determines Cell Fate in Response to Hyperosmotic Stress
KT Farabaugh - 2020 - search.proquest.com
… The material in this chapter is adapted with permission from: Farabaugh, KT, Majumder, M.,
Guan, B.-J., Jobava, R., Wu, J., Krokowski, D., Gao, X.-H., Schuster, A., Longworth, M., Chan, …
Guan, B.-J., Jobava, R., Wu, J., Krokowski, D., Gao, X.-H., Schuster, A., Longworth, M., Chan, …
2022 Herbert Tabor Early Career Investigator Awards: Call for nominations
KT Farabaugh, A Toker, G DeMartino - Journal of Biological Chemistry, 2022 - ASBMB
We can taste the science in the air! There have been a ton of great studies published in JBC
this past year, and it is now that exciting time of year where we ask you, the scientific …
this past year, and it is now that exciting time of year where we ask you, the scientific …
Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator-activated receptor γ (PPARγ) during …
DR Debasish Roy, KT Farabaugh, WJ Wu Jing… - 2017 - cabidigitallibrary.org
The breakdown of stored fat deposits into its components is a highly regulated process that
maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated …
maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated …
Cathodoluminescence spectroscopy of free and bound excitons in chemical-vapor-deposited diamond
LH Robins, EN Farabaugh, A Feldman - Physical Review B, 1993 - APS
Cathodoluminescence (CL) spectroscopy was used to study exciton recombination at
temperatures from 80 to 280 K in undoped and boron-doped diamond particles grown by hot-…
temperatures from 80 to 280 K in undoped and boron-doped diamond particles grown by hot-…