Intraperitoneal injection of the Gram-negative bacterial endotoxin lipopolysaccharide (LPS)
elicits a rapid innate immune response. While this systemic inflammatory response can be …

Inflammation is a pathological hallmark associated with bacterial and viral infections, autoimmune
diseases, genetic disorders, obesity and diabetes, as well as environmental stresses …

The inability of cells to adapt to increased environmental tonicity can lead to inflammatory
gene expression and pathogenesis. The Rel family of transcription factors TonEBP and NF-κB …

The breakdown of stored fat deposits into its components is a highly regulated process that
maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated …

High extracellular osmolarity results in a switch from an adaptive to an inflammatory gene
expression program. We show that hyperosmotic stress activates the protein kinase R (PKR) …

Even just over a century ago, a diagnosis of diabetes was practically a death sentence.
There was no treatment but to attempt to extend the survival of those afflicted via a so-called ‘…

… The material in this chapter is adapted with permission from: Farabaugh, KT, Majumder, M.,
Guan, B.-J., Jobava, R., Wu, J., Krokowski, D., Gao, X.-H., Schuster, A., Longworth, M., Chan, …

We can taste the science in the air! There have been a ton of great studies published in JBC
this past year, and it is now that exciting time of year where we ask you, the scientific …

The breakdown of stored fat deposits into its components is a highly regulated process that
maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated …

Cathodoluminescence (CL) spectroscopy was used to study exciton recombination at
temperatures from 80 to 280 K in undoped and boron-doped diamond particles grown by hot-…