Development and evolution of inner ear sensory epithelia and their innervation

B Fritzsch, KW Beisel, K Jones, I Farinas… - Journal of …, 2002 - Wiley Online Library
The development and evolution of the inner ear sensory patches and their innervation is
reviewed. Recent molecular developmental data suggest that development of these sensory …

The transcriptional landscape of the mammalian genome

…, TL Bailey, M Bansal, L Baxter, KW Beisel… - science, 2005 - science.org
This study describes comprehensive polling of transcription start and termination sites and
analysis of previously unidentified full-length complementary DNAs derived from the mouse …

The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?

B Fritzsch, KW Beisel, LA Hansen - Bioessays, 2006 - Wiley Online Library
… Fritzsch B, Beisel KW. 2001. Evolution and development of the vertebrate ear. … Fritzsch
B, Beisel KW. 2003. Molecular conservation and novelties in vertebrate ear development. …

A type VII myosin encoded by the mouse deafness gene shaker-1

…, P Mburu, A Varela, KA Brown, M Antonio, KW Beisel… - Nature, 1995 - nature.com
GENETIC deafness is common, affecting about 1 in 2,000 births 1 . Many of these show
primary abnormalities of the sensory neuro-epithelia of the inner ear, as do several hearing-…

[HTML][HTML] Molecular evolution of the vertebrate mechanosensory cell and ear

B Fritzsch, KW Beisel, S Pauley… - The International journal …, 2007 - ncbi.nlm.nih.gov
The molecular basis of mechanosensation, mechanosensory cell development and
mechanosensory organ development is reviewed with an emphasis on its evolution. In contrast to …

Cardiac myosin induces myocarditis in genetically predisposed mice.

N Neu, NR Rose, KW Beisel, A Herskowitz… - … (Baltimore, Md.: 1950 …, 1987 - journals.aai.org
After infection with coxsackie virus B3 (CB3), H-2 congenic mice on an A- background
develop immunologically mediated myocarditis associated with an increased titer of myosin …

Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa

…, S Davenport, C Moller, CB Talmadge, KW Beisel… - Science, 1998 - science.org
Usher syndrome type IIa (OMIM 276901), an autosomal recessive disorder characterized by
moderate to severe sensorineural hearing loss and progressive retinitis pigmentosa, maps …

Smaller inner ear sensory epithelia in Neurog1 null mice are related to earlier hair cell cycle exit

…, S Kaing, D Rowitch, KW Beisel… - Developmental …, 2005 - Wiley Online Library
We investigated whether co‐expression of Neurog1 and Atoh1 in common neurosensory
precursors could explain the loss of hair cells in Neurog1 null mice. Analysis of terminal mitosis…

MicroRNA gene expression in the mouse inner ear

MD Weston, ML Pierce, S Rocha-Sanchez, KW Beisel… - Brain research, 2006 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that function through the RNA interference
(RNAi) pathway and post-transcriptionally regulate gene expression in eukaryotic …

Characterization of transcriptomes of cochlear inner and outer hair cells

…, Q Zhang, GA Soukup, KW Beisel… - Journal of …, 2014 - Soc Neuroscience
Inner hair cells (IHCs) and outer hair cells (OHCs) are the two types of sensory receptor
cells that are critical for hearing in the mammalian cochlea. IHCs and OHCs have different …