A multiple Piccolino-RIBEYE interaction supports plate-shaped synaptic ribbons in retinal neurons
TM Müller, K Gierke, A Joachimsthaler… - Journal of …, 2019 - Soc Neuroscience
… Ear pieces taken from rats were digested overnight at 50C in SNET-buffer (400 mm NaCl,
1% SDS, 200 mm Tris, pH 8.0, 5 mm EDTA) containing 10 mg/ml proteinase K. Subsequently, …
1% SDS, 200 mm Tris, pH 8.0, 5 mm EDTA) containing 10 mg/ml proteinase K. Subsequently, …
Analysis of RIM expression and function at mouse photoreceptor ribbon synapses
RAB3A-interacting molecule (RIM) proteins are important regulators of transmitter release
from active zones. At conventional chemical synapses, RIMs contribute substantially to vesicle …
from active zones. At conventional chemical synapses, RIMs contribute substantially to vesicle …
[HTML][HTML] Substitution of valine for histidine 265 in carbon monoxide dehydrogenase from Rhodospirillum rubrum affects activity and spectroscopic states
NJ Spangler, MR Meyers, KL Gierke, RL Kerby… - Journal of Biological …, 1998 - ASBMB
… The K m and K D for CO as well as the K D for cyanide were relatively unchanged as a result
of the amino acid substitution in CODH. The time-dependent reduction of the [Fe 4 S 4 ] 2+ …
of the amino acid substitution in CODH. The time-dependent reduction of the [Fe 4 S 4 ] 2+ …
Signal transmission at invaginating cone photoreceptor synaptic contacts following deletion of the presynaptic cytomatrix protein Bassoon in mouse retina
… Whereas Ca v 1.4-mediated currents in Bsn wt displayed a rather steep voltage dependence
with k~2, this value was increased to k~5 in Bsn ΔEx4/5 cone photoreceptors (Figure 5D,F). …
with k~2, this value was increased to k~5 in Bsn ΔEx4/5 cone photoreceptors (Figure 5D,F). …
[PDF][PDF] Genetic disruption of bassoon in two mutant mouse lines causes divergent retinal phenotypes
… Miriam Ryl, Alexander Urbasik, and Kaspar Gierke contributed equally to this work and …
How to cite this article: Ryl M, Urbasik A, Gierke K, et al. Genetic disruption of bassoon in two …
How to cite this article: Ryl M, Urbasik A, Gierke K, et al. Genetic disruption of bassoon in two …
[HTML][HTML] Functional and structural development of mouse cone photoreceptor ribbon synapses
A Davison, K Gierke, JH Brandstätter… - … & Visual Science, 2022 - jov.arvojournals.org
… To isolate I Ca from K + currents, we used a standard TEA-Cl and cesium-containing
intracellular solution, which has been used previously in mouse photoreceptors. Photoreceptors …
intracellular solution, which has been used previously in mouse photoreceptors. Photoreceptors …
[HTML][HTML] The first synapse in vision in the aging mouse retina
K Gierke, UT Lux, H Regus-Leidig… - Frontiers in Cellular …, 2023 - frontiersin.org
Vision is our primary sense, and maintaining it throughout our lifespan is crucial for our well-being.
However, the retina, which initiates vision, suffers from an age-related, irreversible …
However, the retina, which initiates vision, suffers from an age-related, irreversible …
Controls on in-stream nitrogen loss in western Lake Erie tributaries
RM Kreiling, LA Bartsch, PM Perner, KJ Gierke… - Journal of Great Lakes …, 2024 - Elsevier
Management efforts to reduce cyanobacterial harmful algal blooms (cHABs) in the Great
Lakes have focused on decreasing tributary inputs of phosphorus (P). Recent research has …
Lakes have focused on decreasing tributary inputs of phosphorus (P). Recent research has …
The absence of functional bassoon at cone photoreceptor ribbon synapses affects signal transmission at Off cone bipolar cell contacts in mouse retina
Aim Off cone bipolar cells of the mammalian retina connect to cone photoreceptor synaptic
terminals via non‐invaginating flat contacts at a considerable distance from the only …
terminals via non‐invaginating flat contacts at a considerable distance from the only …
Digoxin disposition kinetics in dogs before and during azotemia.
KD Gierke, D Perrier, M Mayersohn, FI Marcus - Journal of Pharmacology …, 1978 - ASPET
The purpose of this study was to evaluate the disposition kinetics of digoxin after the
administration of a single intravenous dose to the same dogs before and during azotemia. The …
administration of a single intravenous dose to the same dogs before and during azotemia. The …