The neurotrophin, brain-derived neurotrophic factor (BDNF), is essential for synaptic function,
plasticity and neuronal survival. At the axon terminal, when BDNF binds to its receptor, …

Synapse number is the best indicator of cognitive impairment In Alzheimer's disease (AD),
yet the respective contributions of Aβ and tau, particularly human wild-type tau, to synapse …

Growing evidence suggests that soluble Aβ species can drive Alzheimer disease (AD)
pathogenesis by inducing a cascade of events including tau hyperphosphorylation, proteasome …

Calpains are cysteine proteinases that selectively cleave proteins in response to calcium
signals. Exacerbated activation of calpain has been implicated as a major component in the …

As the number of patients with Alzheimer's disease (AD) continues to rise, the need for
efficacious therapeutics is becoming more and more urgent. Understanding the molecular …

Neuronal loss is the most common and critical feature of a spectrum of brain traumas and
neurodegenerative disorders such as Alzheimer’s disease (AD). The capacity to generate new …

We developed a model for the equation of state of fully ionized plasmas which we apply to
hydrogen. Strong coupling effects between ions as well as finite temperature effects for the …

… These experiments have shown good agreement between the predictions of the Saumon-Chabrier
model and the actual data (although there is certainly room for improvement). In …

… In the present calculations, we use the Segretain & Chabrier (1993) spindle diagram,
calculated … We thank MA Wood and B. Hansen for kindly providing models and results from their …

… To calculate Fex , we follow the model developed by Chabrier 8 for fully ionized EIPs. As
long as the ionelectron interaction is weak compared to the kinetic energy of the electrons, Ze2/…