We have examined the incidence and size of infarction after occlusion of different portions of
the rat middle cerebral artery (MCA) in order to define the reliability and predictability of this …

We have evaluated the use of 2,3,5-triphenyltetrazolium chloride (TTC) as an histopathologic
stain for identification of infarcted rat brain tissue. The middle cerebral artery (MCA) of 35 …

… However, DRGs from (-I-) animals did contain cells expressing t&B and MC (Figure 3B), and,
… a novel neurotrophic factor that activates both MC and f&3. Neuron 7, 657-666. Bradley, A (…

The neural stem cell marker CD133 is reported to identify cells within glioblastoma (GBM) that
can initiate neurosphere growth and tumor formation; however, instances of CD133 − cells …

Glial cell line-derived neurotrophic factor (GDNF) exhibits potent effects on survival and
function of midbrain dopaminergic (DA) neurons in a variety of models. Although other growth …

Administration of nerve growth factor (NGF) to aged or lesioned animals has been shown to
reverse the atrophy of basal forebrain cholinergic neurons and ameliorate behavioral deficits…

Accurate and reproducible determination of the size and location of cerebral infarcts is critical
for the evaluation of experimental focal cerebral ischemia. The purpose of this study was to …

Magnetic resonance microscopy (μMRI) is becoming an important tool for non-destructive
analysis of fixed brain tissue. However, unlike MRI, X-ray computed tomography (CT) scans …

Somatic mutation of isocitrate dehydrogenase 1 (IDH1) is now recognized as the most
common initiating event for secondary glioblastoma, a brain tumor type arising with high …

Purpose The extent to which efficacy of the HER2 antibody Trastuzumab in brain metastases
is limited by access of antibody to brain lesions remains a question of significant clinical …