Neuroinflammatory processes play a significant role in the pathogenesis of Parkinson’s disease
(PD). Epidemiologic, animal, human, and therapeutic studies all support the presence of …

Complex dosing regimens, costs, side effects, biodistribution limitations, and variable drug
pharmacokinetic patterns have affected the long-term efficacy of antiretroviral medicines. To …

Stimuli-responsive multimodality imaging agents have broad potential in medical diagnostics.
Herein, we report the development of a new class of branched-bottlebrush polymer dual-…

Single‐voxel proton spectra of the human brain were recorded in five subjects at both 1.5T
and 3.0T using the STEAM pulse sequence. Data acquisition parameters were closely …

Background: Parkinson’s disease is a common progressive neurodegenerative disorder
associated with profound nigrostriatal degeneration. Regrettably, no therapies are currently …

Metal-free magnetic resonance imaging (MRI) agents could overcome the established toxicity
associated with metal-based agents in some patient populations and enable new modes …

Background We posit that the same mononuclear phagocytes (MP) that serve as target cells
and vehicles for a host of microbial infections can be used to improve diagnostics and drug …

The goal of these experiments was to investigate the relationship of ATP, phosphocreatine (PCr),
inorganic phosphate (Pi), monobasic phosphate (H2PO4-), and pH to human muscle …

Background: Previous single voxel 31 P MRS pilot studies of migraine patients have
suggested that disordered energy metabolism or Mg 2+ deficiencies may be responsible for …

Neuronal damage induced by ongoing human immunodeficiency virus type 1 (HIV-1) infection
was investigated in humanized NOD/scid-IL-2Rγ c null mice transplanted at birth with …