Localized neuronal outgrowth induced by long-term sensitization training in Aplysia

ML Wainwright, H Zhang, JH Byrne… - Journal of …, 2002 - Soc Neuroscience
… Immediately after the post-test, animals were anesthetized by injection of isotonic MgCl 2
(500 ml/kg), and both pleural–pedal ganglia were removed. Tail sensory neurons were …

Long-term sensitization training primes Aplysia for further learning

EG Antzoulatos, ML Wainwright, LJ Cleary… - Learning & …, 2006 - learnmem.cshlp.org
Repetitive, unilateral stimulation of Aplysia induces long-term sensitization (LTS) of ipsilaterally
elicited siphon-withdrawal responses. Whereas some morphological effects of training …

Effects of aversive stimuli beyond defensive neural circuits: reduced excitability in an identified neuron critical for feeding in Aplysia

…, C Torno, KM Adams, ML Wainwright… - Learning & …, 2013 - learnmem.cshlp.org
In Aplysia, repeated trials of aversive stimuli produce long-term sensitization (LTS) of defensive
reflexes and suppression of feeding. Whereas the cellular underpinnings of LTS have …

Dissociation of Morphological and Physiological Changes Associated With Long-Term Memory in Aplysia

ML Wainwright, JH Byrne… - Journal of …, 2004 - journals.physiology.org
Neurite outgrowth is a process commonly thought to contribute to long-term learning by
formation of new synaptic contacts. The behavioral effects of long-term sensitization training in …

Role of nitric oxide in the induction of the behavioral and cellular changes produced by a common aversive stimulus in Aplysia

J Farruggella, J Acebo, L Lloyd, ML Wainwright… - Behavioural brain …, 2019 - Elsevier
… In all behavioral experiments, animals were injected systemically with 1 mL per 200-g
body mass of either l-NAME dissolved at a concentration of 20 mg/mL in artificial seawater (ASW), …

Role of serotonin in the lack of sensitization caused by prolonged food deprivation in Aplysia

X Deng, IS Huang, K Williams, ML Wainwright… - Behavioural Brain …, 2024 - Elsevier
… Hemolymph samples (1.5 mL) were collected using a 20-gauge needle and 5-mL syringe.
Hemolymph was withdrawn carefully at a site between the rhinophores and parapodia near …

Change in excitability of a putative decision-making neuron in Aplysia serves as a mechanism in the decision not to feed following food satiation

KJ Dickinson, ML Wainwright, R Mozzachiodi - Behavioural brain research, 2015 - Elsevier
Although decision making is a ubiquitous function, the understanding of its underlying
mechanisms remains limited, particularly at the single-cell level. In this study, we used the …

A novel in vitro analog expressing learning-induced cellular correlates in distinct neural circuits

HA Weisz, ML Wainwright… - Learning & Memory, 2017 - learnmem.cshlp.org
… preparations, 50 mL of 50 µM 5-HT was manually exchanged at a rate of ∼10 mL/min by …
At the end of this period, 5-HT was washed out of with 50 mL of ASW in an identical manner. …

Critical role of protein kinase G in the long-term balance between defensive and appetitive behaviors induced by aversive stimuli in Aplysia

R Chatterji, S Khoury, E Salas, ML Wainwright… - Behavioural brain …, 2020 - Elsevier
This study investigated the signaling cascades involved in the long-term storage of the
balance between defensive and appetitive behaviors observed when the mollusk Aplysia is …

Eat or be eaten? Modifications of Aplysia californica feeding behaviour in response to natural aversive stimuli

KD Wolfe, ML Wainwright, DL Smee, R Mozzachiodi - Animal behaviour, 2016 - Elsevier
Prey often modify their behaviours to diminish predation risk, but the persistence of such
behavioural changes are not well understood. We investigated the effects of predation risk in …