User profiles for M. Brancaccio
Marco BrancaccioLecturer at Imperial College London and Group Leader at UK Dementia Research Institute Verified email at imperial.ac.uk Cited by 2642 |
Generation of circadian rhythms in the suprachiasmatic nucleus
…, ES Maywood, M Brancaccio - Nature Reviews …, 2018 - nature.com
The suprachiasmatic nucleus (SCN) of the hypothalamus is remarkable. Despite numbering
only about 10,000 neurons on each side of the third ventricle, the SCN is our principal …
only about 10,000 neurons on each side of the third ventricle, the SCN is our principal …
Integrin signalling: the tug-of-war in heart hypertrophy
M Brancaccio, E Hirsch, A Notte… - Cardiovascular …, 2006 - academic.oup.com
… protein extending as a spring-like structure from the M to the Z disc. Actin filaments slide
on myosin bundles toward the M disc leading to shortening of the sarcomere and muscle …
on myosin bundles toward the M disc leading to shortening of the sarcomere and muscle …
Circadian pacemaking in cells and circuits of the suprachiasmatic nucleus
MH Hastings, M Brancaccio… - Journal of …, 2014 - Wiley Online Library
The suprachiasmatic nucleus ( SCN ) of the hypothalamus is the principal circadian
pacemaker of the brain. It co‐ordinates the daily rhythms of sleep and wakefulness, as well as …
pacemaker of the brain. It co‐ordinates the daily rhythms of sleep and wakefulness, as well as …
[HTML][HTML] PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and-independent effects
…, L Barberis, G Selvetella, A Maffei, M Brancaccio… - Cell, 2004 - cell.com
The G protein-coupled, receptor-activated phosphoinositide 3-kinase γ (PI3Kγ) mediates
inflammatory responses and negatively controls cardiac contractility by reducing cAMP …
inflammatory responses and negatively controls cardiac contractility by reducing cAMP …
[PDF][PDF] Astrocytes control circadian timekeeping in the suprachiasmatic nucleus via glutamatergic signaling
M Brancaccio, AP Patton, JE Chesham, ES Maywood… - Neuron, 2017 - cell.com
… Here, Brancaccio et al. demonstrate that SCN astrocytes also possess pacemaking properties
and unravel how they set circadian tempo by reciprocal timing with their neuronal partners…
and unravel how they set circadian tempo by reciprocal timing with their neuronal partners…
Melusin, a muscle-specific integrin β1–interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
M Brancaccio, L Fratta, A Notte, E Hirsch, R Poulet… - Nature medicine, 2003 - nature.com
Cardiac hypertrophy is an adaptive response to a variety of mechanical and hormonal
stimuli, and represents an early event in the clinical course leading to heart failure. By gene …
stimuli, and represents an early event in the clinical course leading to heart failure. By gene …
Cell-autonomous clock of astrocytes drives circadian behavior in mammals
M Brancaccio, MD Edwards, AP Patton, NJ Smyllie… - Science, 2019 - science.org
… I suggest the findings of Brancaccio, et al., may be explained by dehydroepiandrosterone
(DHEA) levels. A significant connection of astrocytes and DHEA exists in the literature. It is my …
(DHEA) levels. A significant connection of astrocytes and DHEA exists in the literature. It is my …
[PDF][PDF] A Gq-Ca2+ axis controls circuit-level encoding of circadian time in the suprachiasmatic nucleus
M Brancaccio, ES Maywood, JE Chesham, ASI Loudon… - Neuron, 2013 - cell.com
The role of intracellular transcriptional/post-translational feedback loops (TTFL) within the
circadian pacemaker of the suprachiasmatic nucleus (SCN) is well established. In contrast, …
circadian pacemaker of the suprachiasmatic nucleus (SCN) is well established. In contrast, …
Protection from angiotensin II–mediated vasculotoxic and hypertensive response in mice lacking PI3Kγ
…, M Storto, O Azzolino, M Brancaccio… - The Journal of …, 2005 - rupress.org
Hypertension affects nearly 20% of the population in Western countries and strongly increases
the risk for cardiovascular diseases. In the pathogenesis of hypertension, the vasoactive …
the risk for cardiovascular diseases. In the pathogenesis of hypertension, the vasoactive …
[HTML][HTML] The mammalian circadian timing system and the suprachiasmatic nucleus as its pacemaker
MH Hastings, ES Maywood, M Brancaccio - Biology, 2019 - mdpi.com
The past twenty years have witnessed the most remarkable breakthroughs in our understanding
of the molecular and cellular mechanisms that underpin circadian (approximately one …
of the molecular and cellular mechanisms that underpin circadian (approximately one …