User profiles for M. Creed
 | Meaghan CreedWashington University in St. Louis Verified email at wustl.edu Cited by 2347 |
[HTML][HTML] VTA GABA neurons modulate specific learning behaviors through the control of dopamine and cholinergic systems
The mesolimbic reward system is primarily comprised of the ventral tegmental area (VTA)
and the nucleus accumbens (NAc) as well as their afferent and efferent connections. This …
and the nucleus accumbens (NAc) as well as their afferent and efferent connections. This …
A competitive model for striatal action selection
The direct and indirect pathway striatal medium spiny neurons (dMSNs and iMSNs) have
long been linked to action selection, but the precise roles of these neurons in this process …
long been linked to action selection, but the precise roles of these neurons in this process …
Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders
…, IA Larson, A Modrcin, S Herd, M Creed… - Science translational …, 2014 - science.org
Neurodevelopmental disorders (NDDs) affect more than 3% of children and are attributable
to single-gene mutations at more than 1000 loci. Traditional methods yield molecular …
to single-gene mutations at more than 1000 loci. Traditional methods yield molecular …
Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo
…, B Phillips-Bute, JT Fortney, MR Creed… - The Journal of the …, 2000 - pubs.asahq.org
Background In an era of growing economic constraints on healthcare delivery, anesthesiologists
are increasingly expected to understand cost analysis and evaluate clinical practices. …
are increasingly expected to understand cost analysis and evaluate clinical practices. …
Whole-genome sequencing for identification of Mendelian disorders in critically ill infants: a retrospective analysis of diagnostic and clinical findings
Background Genetic disorders and congenital anomalies are the leading causes of infant
mortality. Diagnosis of most genetic diseases in neonatal and paediatric intensive care units (…
mortality. Diagnosis of most genetic diseases in neonatal and paediatric intensive care units (…
Ventral pallidal modulation of aversion processing
Responding to aversive and rewarding stimuli is essential to survival. The ventral pallidum (VP)
is a critical node in the mesolimbic network, being the primary output of the nucleus …
is a critical node in the mesolimbic network, being the primary output of the nucleus …
Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation
By informing timely targeted treatments, rapid whole-genome sequencing can improve the
outcomes of seriously ill children with genetic diseases, particularly infants in neonatal and …
outcomes of seriously ill children with genetic diseases, particularly infants in neonatal and …
Refining deep brain stimulation to emulate optogenetic treatment of synaptic pathology
Circuit remodeling driven by pathological forms of synaptic plasticity underlies several
psychiatric diseases, including addiction. Deep brain stimulation (DBS) has been applied to treat …
psychiatric diseases, including addiction. Deep brain stimulation (DBS) has been applied to treat …
Reward behaviour is regulated by the strength of hippocampus–nucleus accumbens synapses
Reward drives motivated behaviours and is essential for survival, and therefore there is strong
evolutionary pressure to retain contextual information about rewarding stimuli. This drive …
evolutionary pressure to retain contextual information about rewarding stimuli. This drive …
Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior
The persistence of negative affect in pain leads to co-morbid symptoms such as anhedonia
and depression—major health issues in the United States. The neuronal circuitry and …
and depression—major health issues in the United States. The neuronal circuitry and …