AN2/NG2 protein‐expressing glial progenitor cells in the murine CNS: Isolation, differentiation, and association with radial glia

M DiersFenger, F Kirchhoff, H Kettenmann, JM Levine… - Glia, 2001 - Wiley Online Library
During early neural development, the lineage specification of initially pluripotent progenitor
cells is associated with proliferation, differentiation, and migration. Oligodendroglial …

Patients with active relapsing‐remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: implications for …

…, J Shi, M Grzenkowski, M DiersFenger… - Annals of …, 2000 - Wiley Online Library
M, followed by dissociation through mesh with a pore size of 115 M. Cells were cultured at 4
… sucrose for 3 hours, and embedded in TissuTek (Miles, Elkhart, IN); 8-m cryosections were …

Cell-surface glycoprotein of oligodendrocyte progenitors involved in migration

A Niehaus, J Stegmüller, M Diers-Fenger… - Journal of …, 1999 - Soc Neuroscience
… 150 mmNaCl, 20 mm Tris/HCl, pH 7.4, 1 mm EDTA, 1 mm … of 300 mm NaCl, 20 mmTris/HCl,
pH 7.4, 1 mm EDTA, 1 mm … vol of 0.1m diethylamine, pH 11.5, 1 mm EDTA, 1 mm EGTA, and …

AN2, the mouse homologue of NG2, is a surface antigen on glial precursor cells implicated in control of cell migration

J Stegmüller, S Schneider, A Hellwig, J Garwood… - Journal of …, 2002 - Springer
… Cells staining positive with AN2 antibodies in the murine CNS were found from E13 throughout
development and in the adult (Diers-Fenger et al., 2001) and an analogous distribution …

[HTML][HTML] The proteoglycan NG2 is complexed with α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction …

J Stegmuller, H Werner, KA Nave, J Trotter - Journal of Biological Chemistry, 2003 - ASBMB
The proteoglycan NG2 is expressed by immature glial cells in the developing and adult
central nervous system. Using the COOH-terminal region of NG2 as bait in a yeast two-hybrid …

[HTML][HTML] Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells

…, J Stegmüller, P Schätzle, K Karram, M Koroll… - Journal of biological …, 2008 - ASBMB
Migration of oligodendrocyte precursors along axons is a necessary prerequisite for
myelination, but little is known about underlying mechanisms. NG2 is a large membrane …

Defining the NG2-expressing cell of the adult CNS

PJ Horner, M Thallmair, FH Gage - Journal of neurocytology, 2002 - Springer
… During development, NG2-immunoreactive cells appear to associate with radial glial cells
(Diers-Fenger et al., 2001). In the adult spinal cord it remains to be determined whether NG2 …

[HTML][HTML] Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination

EM Krämer, C Klein, T Koch, M Boytinck… - Journal of Biological …, 1999 - ASBMB
In many cell types, glycosylphosphatidylinositol (GPI)-anchored proteins are sequestered in
detergent-resistant membrane rafts. These are plasma membrane microdomains enriched …

Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development

W Huang, N Zhao, X Bai, K Karram, J Trotter… - Glia, 2014 - Wiley Online Library
NG2 (nerve/glia antigen‐2) is a type I transmembrane glycoprotein and also known as
chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous system, NG2‐…

Mouse NG2+ oligodendrocyte precursors express mRNA for proteolipid protein but not its DM-20 variant: a study of laser microdissection-captured NG2+ cells

P Ye, R Bagnell, AJ D'Ercole - Journal of Neuroscience, 2003 - Soc Neuroscience
Despite recent advances in our understanding of lineage of oligodendrocytes, detailed
molecular characterization of this lineage in vivo is limited, primarily because of our inability to …