AN2/NG2 protein‐expressing glial progenitor cells in the murine CNS: Isolation, differentiation, and association with radial glia
During early neural development, the lineage specification of initially pluripotent progenitor
cells is associated with proliferation, differentiation, and migration. Oligodendroglial …
cells is associated with proliferation, differentiation, and migration. Oligodendroglial …
Patients with active relapsing‐remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: implications for …
…, J Shi, M Grzenkowski, M Diers‐Fenger… - Annals of …, 2000 - Wiley Online Library
… M, followed by dissociation through mesh with a pore size of 115 M. Cells were cultured at 4
… sucrose for 3 hours, and embedded in TissuTek (Miles, Elkhart, IN); 8-m cryosections were …
… sucrose for 3 hours, and embedded in TissuTek (Miles, Elkhart, IN); 8-m cryosections were …
Cell-surface glycoprotein of oligodendrocyte progenitors involved in migration
A Niehaus, J Stegmüller, M Diers-Fenger… - Journal of …, 1999 - Soc Neuroscience
… 150 mmNaCl, 20 mm Tris/HCl, pH 7.4, 1 mm EDTA, 1 mm … of 300 mm NaCl, 20 mmTris/HCl,
pH 7.4, 1 mm EDTA, 1 mm … vol of 0.1m diethylamine, pH 11.5, 1 mm EDTA, 1 mm EGTA, and …
pH 7.4, 1 mm EDTA, 1 mm … vol of 0.1m diethylamine, pH 11.5, 1 mm EDTA, 1 mm EGTA, and …
AN2, the mouse homologue of NG2, is a surface antigen on glial precursor cells implicated in control of cell migration
J Stegmüller, S Schneider, A Hellwig, J Garwood… - Journal of …, 2002 - Springer
… Cells staining positive with AN2 antibodies in the murine CNS were found from E13 throughout
development and in the adult (Diers-Fenger et al., 2001) and an analogous distribution …
development and in the adult (Diers-Fenger et al., 2001) and an analogous distribution …
[HTML][HTML] The proteoglycan NG2 is complexed with α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction …
The proteoglycan NG2 is expressed by immature glial cells in the developing and adult
central nervous system. Using the COOH-terminal region of NG2 as bait in a yeast two-hybrid …
central nervous system. Using the COOH-terminal region of NG2 as bait in a yeast two-hybrid …
[HTML][HTML] Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells
…, J Stegmüller, P Schätzle, K Karram, M Koroll… - Journal of biological …, 2008 - ASBMB
Migration of oligodendrocyte precursors along axons is a necessary prerequisite for
myelination, but little is known about underlying mechanisms. NG2 is a large membrane …
myelination, but little is known about underlying mechanisms. NG2 is a large membrane …
Defining the NG2-expressing cell of the adult CNS
… During development, NG2-immunoreactive cells appear to associate with radial glial cells
(Diers-Fenger et al., 2001). In the adult spinal cord it remains to be determined whether NG2 …
(Diers-Fenger et al., 2001). In the adult spinal cord it remains to be determined whether NG2 …
[HTML][HTML] Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination
EM Krämer, C Klein, T Koch, M Boytinck… - Journal of Biological …, 1999 - ASBMB
In many cell types, glycosylphosphatidylinositol (GPI)-anchored proteins are sequestered in
detergent-resistant membrane rafts. These are plasma membrane microdomains enriched …
detergent-resistant membrane rafts. These are plasma membrane microdomains enriched …
Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development
NG2 (nerve/glia antigen‐2) is a type I transmembrane glycoprotein and also known as
chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous system, NG2‐…
chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous system, NG2‐…
Mouse NG2+ oligodendrocyte precursors express mRNA for proteolipid protein but not its DM-20 variant: a study of laser microdissection-captured NG2+ cells
P Ye, R Bagnell, AJ D'Ercole - Journal of Neuroscience, 2003 - Soc Neuroscience
Despite recent advances in our understanding of lineage of oligodendrocytes, detailed
molecular characterization of this lineage in vivo is limited, primarily because of our inability to …
molecular characterization of this lineage in vivo is limited, primarily because of our inability to …