(Macro)autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …

Objectives: To obtain reliable estimates of the effects of neuraxial blockade with epidural or
spinal anaesthesia on postoperative morbidity and mortality. Design: Systematic review of all …

… A 25% increase in energy consumption was reported after ingestion of PS MPs by M. edulis
(… In M. edulis, the transition of MP from the gut to the haemolymph was observed to continue …

… ) in PBS (150 mm NaCl, 10 mm sodium phosphate buffer, pH … final concentration of 30 μm
inhibitor containing 0.3% DMSO. … with 100 mm 2-mercaptoethanol, 2% SDS, and 62.5 mm Tris-…

mTOR (mammalian target of rapamycin) signalling and macroautophagy (henceforth
autophagy) regulate numerous pathological and physiological processes, including cellular …

… size class; MP SED (kg m −2 ) is the mass of … (m) are the length and width of the stream; m
up (kg m −3 s −1 ) is the advection of suspended MPs from the upstream reach, m down (kg m …

Due to their ubiquitous distribution and chemical composition, microplastics (MPs) are
increasingly being recognized as a global concern. While it is widely acknowledged that MPs in …

Autophagosome elongation Atg5 and Atg12 are involved in the first of two ubiquitylation-like
reactions that control autophagy. Atg12 is conjugated to Atg5 in a reaction that requires …

… The catchment ranges in elevation from 114 to 405 m above sea level (asl). The region was
… The highest postglacial coastline therefore traverses the catchment at approximately 257 m …

Between April to November of 2017, microplastics (MPs) were analysed in biosolids from
two separate suppliers, and in the soils of three agricultural fields to which they were applied, …