[PDF][PDF] Serotonin targets the DAF-16/FOXO signaling pathway to modulate stress responses

B Liang, M Moussaif, CJ Kuan, JJ Gargus, JY Sze - Cell metabolism, 2006 - cell.com
Stress response is a fundamental form of behavioral and physiological plasticity. Here we
describe how serotonin (5HT) governs stress behavior by regulating DAF-2 insulin/IGF-1 …

Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

J Wang, H Dai, N Yousaf, M Moussaif… - … and cellular biology, 1999 - Am Soc Microbiol
… The cell-permeable Grb10 fusion peptide was purified by affinity chromatography on a
nickel column (Novagen) and eluted with 0.4 M imidazole in the presence of 6 M urea. The …

SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease

…, AL Oblak, J Javens‐Wolfe, M Moussaif… - … Research & Clinical …, 2023 - Wiley Online Library
INTRODUCTION The risk of developing Alzheimer's disease is associated with genes involved
in microglial function. Inositol polyphosphate‐5‐phosphatase (INPP5D), which encodes …

[HTML][HTML] RFX Transcription Factor DAF-19 Regulates 5-HT and Innate Immune Responses to Pathogenic Bacteria in Caenorhabditis elegans

Y Xie, M Moussaif, S Choi, L Xu, JY Sze - PLoS genetics, 2013 - journals.plos.org
… Contributed equally to this work with: Yusu Xie, Mustapha Moussaif … Mustapha
Moussaif , Contributed equally to this work with: Yusu Xie, Mustapha Moussaif

Probing the mechanism of rhodopsin‐catalyzed transducin activation

M Natochin, M Moussaif… - Journal of …, 2001 - Wiley Online Library
… Filters were washed three times with 20 mm Tris−HCl (pH 8.0) buffer containing 130 mm
NaCl and 10 mm MgSO 4 and counted in a liquid scintillation counter. In some experiments, 10 …

Cyclosporin C is the main antifungal compound produced by Acremonium luzulae

M Moussaïf, P Jacques, P Schaarwächter… - Applied and …, 1997 - Am Soc Microbiol
… The supernatant was then filtered through a preweighed filter (0.45 m; HA Millipore) and …
phase column (internal diameter, 4 mm; packed with 5-m C18 and maintained at 60C on a 4 …

[HTML][HTML] Transducin activation state controls its light-dependent translocation in rod photoreceptors

V Kerov, D Chen, M Moussaif, YJ Chen… - Journal of Biological …, 2005 - ASBMB
… ) were homogenized in the dark by sonication in 400 μl of 20 mm Hepes buffer (pH = 8.0),
containing 100 mm NaCl and 4 mm MgSO 4 . Aliquots of retinal homogenates (15 μl) were …

Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans

…, B Ashokkumar, M Moussaif… - … of Physiology-Cell …, 2007 - journals.physiology.org
Two putative orthologs to the human reduced folate carrier (hRFC), folt-1 and folt-2, which
share a 40 and 31% identity, respectively, with the hRFC sequence, have been identified in …

Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D

…, TTC Yang, XY Yang, J Zhang, M Moussaif… - … and cellular biology, 2010 - Taylor & Francis
Calcineurin is a widely expressed and highly conserved Ser/Thr phosphatase. Calcineurin is
inhibited by the immunosuppressant drug cyclosporine A (CsA) or tacrolimus (FK506). The …

[HTML][HTML] Rhodopsin determinants for transducin activation: a gain-of-function approach

M Natochin, KG Gasimov, M Moussaif… - Journal of Biological …, 2003 - ASBMB
… light and then bleached for 30 s before the addition of 20 μm [ 35 S]GTPγS (2 Ci/mmol). At …
ml of 50 mm Tris-HCl (pH 7.5) buffer containing 100 mm NaCl, 4 mm MgSO 4 , and 1 mm GTP. …