Inflammatory mediators in the elderly
KS Krabbe, M Pedersen, H Bruunsgaard - Experimental gerontology, 2004 - Elsevier
Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …
Inflammatory microenvironment remodelling by tumour cells after radiotherapy
M McLaughlin, EC Patin, M Pedersen, A Wilkins… - Nature Reviews …, 2020 - nature.com
The development of immune checkpoint inhibitors (ICIs) is revolutionizing the way we think
about cancer treatment. Even so, for most types of cancer, only a minority of patients currently …
about cancer treatment. Even so, for most types of cancer, only a minority of patients currently …
Synthetic aperture ultrasound imaging
JA Jensen, SI Nikolov, KL Gammelmark, MH Pedersen - Ultrasonics, 2006 - Elsevier
… A full image can be made by combining all emissions, which can be from 1 to M or from 2
to M and 1. The new emission 1 can, thus, replace the old emission 1, which can be done by …
to M and 1. The new emission 1 can, thus, replace the old emission 1, which can be done by …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
…, CB Pedersen, MG Pedersen, RE Peterson… - Nature …, 2018 - nature.com
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
…, J Pallesen, DS Palmer, CB Pedersen, MG Pedersen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
Identification of common genetic risk variants for autism spectrum disorder
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
[PDF][PDF] The matrix cookbook
KB Petersen, MS Pedersen - Technical University of Denmark, 2008 - ece.uwaterloo.ca
… where L, M are unique unit lower triangular matrices and D is a unique diagonal matrix. …
The (normal) Inverse Wishart distribution for M 2 RP ⇥P , M is positive definite, where m can be …
The (normal) Inverse Wishart distribution for M 2 RP ⇥P , M is positive definite, where m can be …
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
…, M Bækvad-Hansen, PB Mortensen, CB Pedersen… - Nature …, 2018 - nature.com
Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
Genome-wide association study identifies 30 loci associated with bipolar disorder
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
…, RD Oades, DS Palmer, CB Pedersen, MG Pedersen… - Cell, 2019 - cell.com
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …