Response of rubrospinal and corticospinal neurons to injury and neurotrophins
W Tetzlaff, NR Kobayashi, KMG Giehl, BJ Tsui… - Progress in brain …, 1994 - Elsevier
Publisher Summary This chapter focuses on problems, such as (1) the neuronal death or
severe atrophy occurring in many axotomized central nervous system (CNS) and (2) the failure …
severe atrophy occurring in many axotomized central nervous system (CNS) and (2) the failure …
A dermal niche for multipotent adult skin-derived precursor cells
…, J Biernaskie, A Junek, NR Kobayashi… - Nature cell …, 2004 - nature.com
A fundamental question in stem cell research is whether cultured multipotent adult stem cells
represent endogenous multipotent precursor cells. Here we address this question, focusing …
represent endogenous multipotent precursor cells. Here we address this question, focusing …
BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal …
NR Kobayashi, DP Fan, KM Giehl… - Journal of …, 1997 - Soc Neuroscience
… of GAP-43 in uninjured RSNs (NR Kobayashi and W. Tetzlaff, unpublished observation); thus…
In contrast, BDNF infusion increased Tα1-tubulin expression in intact RSNs (NR Kobayashi …
In contrast, BDNF infusion increased Tα1-tubulin expression in intact RSNs (NR Kobayashi …
Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury
…, J Liu, C Messerer, NR Kobayashi… - Proceedings of the …, 2002 - National Acad Sciences
Scientific interest to find a treatment for spinal cord injuries has led to the development of
numerous experimental strategies to promote axonal regeneration across the spinal cord injury …
numerous experimental strategies to promote axonal regeneration across the spinal cord injury …
Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue …
E Stewart, NR Kobayashi, MJ Higgins… - … Engineering Part C …, 2015 - liebertpub.com
… Nao Kobayashi, a remarkable colleague and cherished friend. Nao's passion and dedication
to her scholarship was unparalleled and her friendship and caring spirit will be missed. …
to her scholarship was unparalleled and her friendship and caring spirit will be missed. …
Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy
NR Kobayashi, AM Bedard, MT Hincke… - European Journal of …, 1996 - Wiley Online Library
Motoneurons of the adult survive after axotomy even though they are deprived of putative
target derived trophic factors. Alternative sources of trophic support may substitute. In this study …
target derived trophic factors. Alternative sources of trophic support may substitute. In this study …
Analysis of the neurogenic potential of multipotent skin-derived precursors
KJL Fernandes, NR Kobayashi, CJ Gallagher… - Experimental …, 2006 - Elsevier
Multipotent precursors similar to stem cells of the embryonic neural crest (NC) have been
identified in several postnatal tissues, and are potentially useful for research and therapeutic …
identified in several postnatal tissues, and are potentially useful for research and therapeutic …
G-protein coupled receptors in stem cell self-renewal and differentiation
NR Kobayashi, SM Hawes, JM Crook… - Stem Cell Reviews and …, 2010 - Springer
Stem cells have great potential for understanding early development, treating human disease,
tissue trauma and early phase drug discovery. The factors that control the regulation of …
tissue trauma and early phase drug discovery. The factors that control the regulation of …
[HTML][HTML] Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates …
Introduction Despite attempts to prevent brain injury during the hyperacute phase of stroke,
most sufferers end up with significant neuronal loss and functional deficits. The use of cell-…
most sufferers end up with significant neuronal loss and functional deficits. The use of cell-…
Human stem cells for modeling neurological disorders: accelerating the drug discovery pipeline
JM Crook, NR Kobayashi - Journal of cellular biochemistry, 2008 - Wiley Online Library
The availability of human stem cells heralds a new era for modeling normal and pathologic
tissues and developing therapeutics. For example, the in vitro recapitulation of normal and …
tissues and developing therapeutics. For example, the in vitro recapitulation of normal and …