A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology
JF Nelson, LS Felicio, PK Randall, C Sims… - Biology of …, 1982 - academic.oup.com
Cycle frequency, length, and vaginal cytology were measured longitudinally in three cohorts
of singly housed virgin mice staggered across a 3-year interval. The age profiles of these …
of singly housed virgin mice staggered across a 3-year interval. The age profiles of these …
Drinking to cope, emotional distress and alcohol use and abuse: a ten-year model.
…, CK Holahan, RC Cronkite, PK Randall - Journal of studies on …, 2001 - jsad.com
Objective: This study examines the ability of baseline drinking to cope to predict drinking
behavior across an ensuing 10-year period. In addition, it examines whether a propensity to …
behavior across an ensuing 10-year period. In addition, it examines whether a propensity to …
Effect of naltrexone and ondansetron on alcohol cue–induced activation of the ventral striatum in alcohol-dependent people
…, X Li, S Henderson, PK Randall… - Archives of general …, 2008 - jamanetwork.com
Context Medication for the treatment of alcoholism is currently not particularly robust.
Neuroimaging techniques might predict which medications could be useful in the treatment of …
Neuroimaging techniques might predict which medications could be useful in the treatment of …
A double‐blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal
H Myrick, R Malcolm, PK Randall… - Alcoholism: Clinical …, 2009 - Wiley Online Library
Introduction: Some anticonvulsants ameliorate signs and symptoms of alcohol withdrawal,
but have an unacceptable side effect burden. Among the advantages of using anticonvulsant …
but have an unacceptable side effect burden. Among the advantages of using anticonvulsant …
[HTML][HTML] Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals
Alcohol dependence is characterized by tolerance, physical dependence, and craving. The
neuroadaptations underlying these effects of chronic alcohol abuse are likely due to altered …
neuroadaptations underlying these effects of chronic alcohol abuse are likely due to altered …
Drinking to cope and alcohol use and abuse in unipolar depression: a 10-year model.
…, CK Holahan, RC Cronkite, PK Randall - Journal of abnormal …, 2003 - psycnet.apa.org
This study examined drinking to cope with distress and drinking behavior in a baseline
sample of 412 unipolar depressed patients assessed 4 times over a 10-year period. Baseline …
sample of 412 unipolar depressed patients assessed 4 times over a 10-year period. Baseline …
[HTML][HTML] Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in …
…, MF Lopez, PK Randall… - …, 2014 - nature.com
The prefrontal cortex (PFC) is a brain region that is critically involved in cognitive function
and inhibitory control of behavior, and adolescence represents an important period of …
and inhibitory control of behavior, and adolescence represents an important period of …
Gabapentin combined with naltrexone for the treatment of alcohol dependence
…, AM Baros, LR Waid, PK Randall - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: Naltrexone, an efficacious medication for alcohol dependence, does not work for
everyone. Symptoms such as insomnia and mood instability that are most evident during …
everyone. Symptoms such as insomnia and mood instability that are most evident during …
An examination of the decline in fear and disgust during exposure-based treatment
It has been suggested that disgust plays a prominent role in the fear of spiders. Participants (N=27)
displaying marked spider fear were provided 30min of self-directed in vivo exposure …
displaying marked spider fear were provided 30min of self-directed in vivo exposure …
A double‐blind placebo‐controlled trial of N‐acetylcysteine in the treatment of cocaine dependence
…, PW Kalivas, JS Nicholas, PK Randall… - … American journal on …, 2013 - Wiley Online Library
Background There remains no FDA approved medication for the treatment of cocaine
dependence. Preclinical studies and early pilot clinical investigations have suggested that N‐…
dependence. Preclinical studies and early pilot clinical investigations have suggested that N‐…