User profiles for P. Kaifosh

Patrick Kaifosh

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Cited by 3449

Regulation of neuronal input transformations by tunable dendritic inhibition

M Lovett-Barron, GF Turi, P Kaifosh, PH Lee… - Nature …, 2012 - nature.com
Transforming synaptic input into action potential output is a fundamental function of neurons.
The pattern of action potential output from principal cells of the mammalian hippocampus …

Dendritic inhibition in the hippocampus supports fear learning

M Lovett-Barron, P Kaifosh, MA Kheirbek, N Danielson… - Science, 2014 - science.org
Fear memories guide adaptive behavior in contexts associated with aversive events. The
hippocampus forms a neural representation of the context that predicts aversive events. …

[PDF][PDF] Distinct contribution of adult-born hippocampal granule cells to context encoding

NB Danielson, P Kaifosh, JD Zaremba, M Lovett-Barron… - Neuron, 2016 - cell.com
… Spatial Information in abGCs (A) For each cell firing at least four running-related transients,
we calculated the spatial information p value and tuning specificity p value by shuffling the …

[PDF][PDF] Sublayer-specific coding dynamics during spatial navigation and learning in hippocampal area CA1

NB Danielson, JD Zaremba, P Kaifosh, J Bowler… - Neuron, 2016 - cell.com
… We modeled the mouse’s task performance P as a linear combination of DD, DS, and t (DD,
mean distance to reward in the deep sublayer; DS, mean distance to reward in the …

[HTML][HTML] SIMA: Python software for analysis of dynamic fluorescence imaging data

P Kaifosh, JD Zaremba, NB Danielson… - Frontiers in …, 2014 - frontiersin.org
… Given this model, when a subset P t of the pixels are imaged in the frame taken at time t,
the … as the entries of the pseudo-inverse of the matrix with entries a pi for all pixels p in P t . …

A 2D, fully-coupled, hydro-mechanical, FDEM formulation for modelling fracturing processes in discontinuous, porous rock masses

A Lisjak, P Kaifosh, L He, BSA Tatone… - Computers and …, 2017 - Elsevier
This paper presents a new, fully-coupled, hydro-mechanical (HM) formulation for a finite-discrete
element method computer code. In the newly-developed, hydraulic solver, fluid flow is …

A temporal basis for predicting the sensory consequences of motor commands in an electric fish

A Kennedy, G Wayne, P Kaifosh, K Alviņa… - Nature …, 2014 - nature.com
… input being of E, M, L and P type are given by P E , P M , P L and P P , with P E + P M + … for
p l and p p = 3, 5, 7, and 9%. The rate of cancellation was slightly lower for p l = p p = 1%, but …

Septo-hippocampal GABAergic signaling across multiple modalities in awake mice

P Kaifosh, M Lovett-Barron, GF Turi, TR Reardon… - Nature …, 2013 - nature.com
Hippocampal interneurons receive GABAergic input from the medial septum. Using two-photon
Ca 2+ imaging of axonal boutons in hippocampal CA1 of behaving mice, we found that …

Acceleration of a 2D/3D finite-discrete element code for geomechanical simulations using General Purpose GPU computing

…, OK Mahabadi, L He, BSA Tatone, P Kaifosh… - Computers and …, 2018 - Elsevier
This paper presents a novel implementation of a hydro-mechanically coupled, finite-discrete
element method (FDEM) optimized to exploit the computing parallelism of graphics …

Impaired hippocampal place cell dynamics in a mouse model of the 22q11. 2 deletion

…, NB Danielson, AD Grosmark, PW Kaifosh… - Nature …, 2017 - nature.com
… Specifically, the initial analysis revealed significant differences for Conditions II (P = 0.028)
and III (P = 0.0008) among the two genotypes (for formulas, see Online Methods). We found …