Phosphorylated products of phosphatidylinositol play critical roles in the regulation of membrane
traffic, in addition to their classical roles as second messengers in signal transduction at …

The DENN domain is a common, evolutionarily ancient, and conserved protein module, yet
it has gone largely unstudied; until recently, little was known regarding its functional roles. …

Intracellular Ca2+ pools play a critical role in the regulation of the free cytosolic Ca2+
concentration and subsequent cellular activity in a wide variety of cell types. The storage and …

… Membrane fractions (P, and LP) were prepared from rat brain homogenates as described".
The Pfraction, which is enriched in intact nerve terminal membranes (synaptosomes), was …

SYNAPTOJANIN is a nerve terminal protein of relative molecular mass 145,000 which
appears to participate with dynamin in synaptic vesicle recycling 1,2 . The central region of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …

Synapses are fundamental information-processing units of the brain, and synaptic dysregulation
is central to many brain disorders ("synaptopathies"). However, systematic annotation of …

… P. McPherson). Secondary antibodies were rabbit anti-goat Cy5 (1:120; Zymed); goat anti-mouse
Cy5 (1:1,500; Amersham), goat anti-mouse tetramethylmodamine (TMR) (1:400), and …

We examined the release of cardiac troponin T (cTnT) and I (cTnI) into the blood of patients
after acute myocardial infarction (AMI). Three postAMI serum samples were applied in …

Ca2+ release from inositol 1,4,5-trisphosphate (IP3)-sensitive and ryanodine-sensitive
intracellular Ca2+ stores is mediated by distinct proteins identified as IP3 receptors (IP3R) and …