User profiles for R. A. Doan
Ryan A DoanPhD Candidate at The Vollum Institute | OHSU Verified email at ohsu.edu Cited by 533 |
Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice
Peripheral polyneuropathy is a common and dose-limiting side effect of many important
chemotherapeutic agents. Most such neuropathies are characterized by early axonal …
chemotherapeutic agents. Most such neuropathies are characterized by early axonal …
[HTML][HTML] Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program
Chemotherapy-induced peripheral neuropathy is one of the most prevalent dose-limiting
toxicities of anticancer therapy. Development of effective therapies to prevent chemotherapy-…
toxicities of anticancer therapy. Development of effective therapies to prevent chemotherapy-…
[HTML][HTML] Gene therapy targeting SARM1 blocks pathological axon degeneration in mice
Axonal degeneration (AxD) following nerve injury, chemotherapy, and in several neurological
disorders is an active process driven by SARM1, an injury-activated NADase. Axons of …
disorders is an active process driven by SARM1, an injury-activated NADase. Axons of …
[BOOK][B] THE MILLER HERESY, MILLENNIALISM AND AMERICAN CULTURE (RELIGION, ANTEBELLUM)
RA Doan - 1984 - search.proquest.com
William Miller and his adventist followers predicted that Christ would return in 1843 in fulfillment
of biblical prophecy. This expectation was so much at odds with the secular boosterism …
of biblical prophecy. This expectation was so much at odds with the secular boosterism …
TMEM184b promotes axon degeneration and neuromuscular junction maintenance
Complex nervous systems achieve proper connectivity during development and must maintain
these connections throughout life. The processes of axon and synaptic maintenance and …
these connections throughout life. The processes of axon and synaptic maintenance and …
Glia in the skin activate pain responses
RA Doan, KR Monk - Science, 2019 - science.org
The ability to rapidly perceive and react to damaging stimuli is essential for survival. In the
vertebrate nervous system, specialized neural crest–derived sensory neurons in the skin, …
vertebrate nervous system, specialized neural crest–derived sensory neurons in the skin, …
[HTML][HTML] Dock1 acts cell-autonomously in Schwann cells to regulate the development, maintenance, and repair of peripheral myelin
RA Doan, KR Monk - bioRxiv, 2023 - ncbi.nlm.nih.gov
Schwann cells, the myelinating glia of the peripheral nervous system (PNS), are critical for
myelin development, maintenance, and repair. Rac1 is a known regulator of radial sorting, a …
myelin development, maintenance, and repair. Rac1 is a known regulator of radial sorting, a …
[BOOK][B] Green gold to the emerald shores: Irish immigration to the United States and transatlantic monetary aid, 1854-1923
RA Doan - 1999 - search.proquest.com
Following the Great Irish Potato Famine (1846–1851), Catholic emigration from Ireland
became a virtual institution. Over one million persons emigrated during the Famine, and, in the …
became a virtual institution. Over one million persons emigrated during the Famine, and, in the …
The quantitative reasoning program at Hollins University
CL Diefenderfer, RA Doan, C Salowey - Peer Review, 2004 - go.gale.com
In the fall of 1998, Hollins University undertook a major overhaul of its general education
program. The new requirements, approved in 2001, allow for foundational work in selected …
program. The new requirements, approved in 2001, allow for foundational work in selected …
Southern Cross: The Beginnings of the Bible Belt
RA Doan - 1998 - JSTOR
Christine Leigh Heyrman's Southern Cross builds on research both broad and deep to construct
a richly textured portrait of southern evangelicalism from the late eighteenth to the early …
a richly textured portrait of southern evangelicalism from the late eighteenth to the early …