Prolonged monitoring studies of patients with infantile spasms have shown that hypsarrhythmia
is a highly variable and dynamic electroencephalographic pattern. Variations of the …

With the use of a time‐synchronized video and polygraphic recording system, 5,042 infantile
spasms were monitored and analyzed in 24 infants aged 1 to 43 months. Of these, 33.9% …

Twenty-four patients with infantile spasms were entered in a double-blind, placebo-controlled,
crossover study to compare the therapeutic effectiveness of ACTH (20 to 30 units/day) …

Infantile spasms is a unique disorder peculiar to infancy and early childhood. In this article,
the clinical manifestations and electroencephalographic features of the disorder are …

Fifty patients in whom the diagnosis of infantile spasms had recently been made and who
had hypsarrhythmic electroencephalographic findings were randomly assigned to receive …

Infantile spasms syndrome (ISS) is a catastrophic pediatric epilepsy with motor spasms,
persistent seizures, mental retardation, and in some cases, autism. One of its monogenic causes …

… region receives inputs from widespread brain areas, and so the brainstem dysfunction
could possibly be secondary to a primary disturbance located in some other region ( Hrachovy …

We report the long-term outcome of 64 infants with infantile spasms, followed prospectively,
using controlled treatment schedules and objective techniques (24-hour EEG and video …

PURPOSE: Depression is a highly prevalent, relatively underdiagnosed and undertreated
comorbid condition in epilepsy. The purpose of this study was to determine the effect of using …

Sleep staging was performed on 32 patients with infantile spasms. All patients demonstrated
significantly less total sleep time and lower percentage of REM time than the expected …