SER-7, a Caenorhabditis elegans 5-HT7-like Receptor, Is Essential for the 5-HT Stimulation of Pharyngeal Pumping and Egg Laying

…, KL Buehrer, PR Komuniecki, RW Komuniecki - Genetics, 2006 - academic.oup.com
Serotonin (5-HT) stimulates both pharyngeal pumping and egg laying in Caenorhabditis
elegans. Four distinct 5-HT receptors have been partially characterized, but little is known about …

Tyramine and octopamine independently inhibit serotonin-stimulated aversive behaviors in Caenorhabditis elegans through two novel amine receptors

…, J Gray, PR Komuniecki, RW Komuniecki - Journal of …, 2007 - Soc Neuroscience
… and RW Komuniecki, unpublished results). TYRA-3 clustered most closely with a recently
identified TA-specific insect GPCR that activates Ca 2+ -dependent chloride channels after …

SER‐7b, a constitutively active Gαs coupled 5‐HT7‐like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron

…, J Geng, AD Gray, RW Komuniecki - Journal of …, 2003 - Wiley Online Library
Serotonin plays a key role in the regulation of pharyngeal pumping in nematodes. We have
isolated a Caenorhabditis elegans cDNA (C09B7.1b, ser‐7b) with greatest identity to the 5‐…

The monoaminergic modulation of sensory-mediated aversive responses in Caenorhabditis elegans requires glutamatergic/peptidergic cotransmission

…, A Korchnak, RW Komuniecki - Journal of …, 2010 - Soc Neuroscience
Monoamines and neuropeptides interact to modulate behavioral plasticity in both vertebrates
and invertebrates. In Caenorhabditis elegans behavioral state or “mood” is dependent on …

Three distinct amine receptors operating at different levels within the locomotory circuit are each essential for the serotonergic modulation of chemosensation in …

…, R Steven, B Bamber, RW Komuniecki - Journal of …, 2009 - Soc Neuroscience
Serotonin modulates behavioral plasticity in both vertebrates and invertebrates and in
Caenorhabditis elegans regulates key behaviors, including locomotion, aversive learning and …

Dual Excitatory and Inhibitory Serotonergic Inputs Modulate Egg Laying in Caenorhabditis elegans

…, G Harris, C Condon, P Komuniecki, RW Komuniecki - Genetics, 2009 - academic.oup.com
… that SER-4 and MOD-1 provide inhibitory input into the egg-laying process (Komuniecki
Komuniecki, unpublished results). The heterologous expression of SER-5 may problematic; for …

A Genetic Survey of Fluoxetine Action on Synaptic Transmission in Caenorhabditis elegans

…, S Miller, CJ Kuan, VM Hapiak, RW Komuniecki… - Genetics, 2010 - academic.oup.com
Fluoxetine is one of the most commonly prescribed medications for many behavioral and
neurological disorders. Fluoxetine acts primarily as an inhibitor of the serotonin reuptake …

Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?

RW Komuniecki, RJ Hobson, EB Rex… - Molecular and …, 2004 - Elsevier
… elegans is toxic, suggesting that SER-7 agonists may be useful anthelminthics (Hobson
and Komuniecki, unpublished). ESTs for putative SER-7 homologues have been identified in …

Multiple sensory inputs are extensively integrated to modulate nociception in C. elegans

…, GP Harris, BA Bamber, RW Komuniecki - Journal of …, 2015 - Soc Neuroscience
Sensory inputs are integrated extensively before decision making, with altered multisensory
integration being associated with disorders such as autism. We demonstrate that the two C. …

[BOOK][B] Molecular medical parasitology

J Marr, TW Nilsen, RW Komuniecki - 2002 - books.google.com
A valuable, new source, Molecular Medical Parasitology is the only text of its kind--one that
applies broad concepts and current scientific advances from both molecular biology and …