Therapeutics of Alzheimer's disease: Past, present and future
Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …
Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage
KP Mollen, RJ Anand, A Tsung, JM Prince, RM Levy… - Shock, 2006 - journals.lww.com
… evidence that hepatic injury in I/R is TLR4 dependent but also … for the hepatic injury sustained
during I/R ( 34 ). This finding is … sterile I/R injury in the liver. The TLR4-dependent nature of I/…
during I/R ( 34 ). This finding is … sterile I/R injury in the liver. The TLR4-dependent nature of I/…
The role of the intestinal barrier in the pathogenesis of necrotizing enterocolitis
RJ Anand, CL Leaphart, KP Mollen, DJ Hackam - Shock, 2007 - journals.lww.com
Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease
in neonates and is increasing in frequency because of recent advances in neonatal care. …
in neonates and is increasing in frequency because of recent advances in neonatal care. …
Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study
…, R Anand, A Cicin-Sain, R Ferrara, R Spiegel - The Lancet, 2000 - thelancet.com
Background Dementia with Lewy bodies is a common form of dementia in the elderly,
characterised clinically by fluctuating cognitive impairment, attention deficits, visual hallucinations, …
characterised clinically by fluctuating cognitive impairment, attention deficits, visual hallucinations, …
Clozapine treatment for suicidality in schizophrenia: international suicide prevention trial (InterSePT)
…, AI Green, AC Altamura, R Anand… - Archives of general …, 2003 - jamanetwork.com
Background Approximately 50% of patients with schizophrenia or schizoaffective disorder
attempt suicide, and approximately 10% die of suicide. Study results suggest that clozapine …
attempt suicide, and approximately 10% die of suicide. Study results suggest that clozapine …
Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trialCommentary: Another piece of the Alzheimer's jigsaw
M Rösler, T Bayer, R Anand, A Cicin-Sain, S Gauthier… - Bmj, 1999 - bmj.com
Objectives: To assess the effects of rivastigmine on the core domains of Alzheimer9s disease.
Design: Prospective, randomised, multicentre, double blind, placebo controlled, parallel …
Design: Prospective, randomised, multicentre, double blind, placebo controlled, parallel …
A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones
…, R Finniear, D Jenner, S Powell, R Anand… - Nucleic acids …, 1990 - academic.oup.com
The recent development of yeast artificial chromosome (YAC) vectors has provided a system
for cloning fragments that are over ten times larger than those that can be cloned in more …
for cloning fragments that are over ten times larger than those that can be cloned in more …
Effect of convalescent plasma on organ support–free days in critically ill patients with COVID-19: a randomized clinical trial
…, K Amenyah, M Ammoun, R Anand, SP Anand… - Jama, 2021 - jamanetwork.com
Importance The evidence for benefit of convalescent plasma for critically ill patients with
COVID-19 is inconclusive. Objective To determine whether convalescent plasma would improve …
COVID-19 is inconclusive. Objective To determine whether convalescent plasma would improve …
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
Mitochondrial fusion and structure depend on the dynamin-like GTPase OPA1, whose activity
is regulated by proteolytic processing. Constitutive OPA1 cleavage by YME1L and OMA1 …
is regulated by proteolytic processing. Constitutive OPA1 cleavage by YME1L and OMA1 …
Effect of metal based additive on performance emission and combustion characteristics of diesel engine fuelled with biodiesel
GR Kannan, R Karvembu, R Anand - Applied energy, 2011 - Elsevier
This study investigates the use of ferric chloride (FeCl 3 ) as a fuel borne catalyst (FBC) for
waste cooking palm oil based biodiesel. The metal based additive was added to biodiesel at …
waste cooking palm oil based biodiesel. The metal based additive was added to biodiesel at …