Serotonin (5-HT) is a major modulator of the CNS. In motoneurons recorded in slices of the
spinal cord, 5-HT promotes plateau potentials mediated by the activity of low-threshold L-type …

It has been recently proposed that a5-subunit containing GABAA receptors (a5-GABAA
receptors) that mediate tonic inhibition might be involved in pain. The purpose of this study was …

Voltage-gated T-type Ca 2+ (Ca V 3) channels regulate diverse physiological events, including
neuronal excitability, and have been linked to several pathological conditions such as …

Extrasynaptic α 5 ‐subunit containing GABA A (α 5 ‐GABA A ) receptors participate in chronic
pain. Previously, we reported a sex difference in the action of α 5 ‐GABA A receptors in …

The effect of a brief train of electric stimuli in the dorsolateral funiculus on the intrinsic response
properties of turtle motoneurones was investigated in transverse sections of the spinal …

Key points GABA is an essential molecule for sensory information processing. It is usually
assumed to be released by neurons. Here we show that in the dorsal horn of the spinal cord, …

The chronification of pain can be attributed to changes in membrane receptors and channels
underlying neuronal plasticity and signal transduction largely within nociceptive neurons …

The role of spinal α 5 subunit-containing GABA A (α 5 -GABA A ) receptors in chronic pain is
controversial. The purpose of this study was to investigate the participation of spinal α 5 -…

Background Calcium-activated chloride channels (CaCCs) activation induces membrane
depolarization by increasing chloride efflux in primary sensory neurons that can facilitate …

… [138] Bautista W, Aguilar J, Loeza-Alcocer JE, Delgado-Lezama R. Preand postsynaptic
modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord. J Physiol 2010; 588…