User profiles for R. Gombos
Rita GombosBiological Research Centre, Szeged Verified email at brc.hu Cited by 439 |
Formin proteins of the DAAM subfamily play a role during axon growth
T Matusek, R Gombos, A Szécsényi… - Journal of …, 2008 - Soc Neuroscience
The regulation of growth cone actin dynamics is a critical aspect of axonal growth control.
Among the proteins that are directly involved in the regulation of actin dynamics, actin …
Among the proteins that are directly involved in the regulation of actin dynamics, actin …
[PDF][PDF] Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens
The co-engagement of fragment crystallizable (Fc) gamma receptors (FcγRs) with the Fc
region of recombinant immunoglobulin monoclonal antibodies (mAbs) and its contribution to …
region of recombinant immunoglobulin monoclonal antibodies (mAbs) and its contribution to …
[PDF][PDF] PI3K/Akt cooperates with oncogenic notch by inducing nitric oxide-dependent inflammation
SN Villegas, R Gombos, L García-López… - Cell reports, 2018 - cell.com
… compound causing a response greater than 20% was re-screened (198 suppressor and
276 enhancer compounds) (Figure S1D) using a larger number of animals (n = 60 larvae/drug/R…
276 enhancer compounds) (Figure S1D) using a larger number of animals (n = 60 larvae/drug/R…
Efficiency of cell-free and cell-associated virus in mucosal transmission of human immunodeficiency virus type 1 and simian immunodeficiency virus
…, SL Hulot, B Korioth-Schmitz, RB Gombos… - Journal of …, 2013 - Am Soc Microbiol
Effective strategies are needed to block mucosal transmission of human immunodeficiency
virus type 1 (HIV-1). Here, we address a crucial question in HIV-1 pathogenesis: whether …
virus type 1 (HIV-1). Here, we address a crucial question in HIV-1 pathogenesis: whether …
Harnessing co-stimulatory TNF receptors for cancer immunotherapy: current approaches and future opportunities
JD Waight, RB Gombos, NS Wilson - Human Antibodies, 2017 - content.iospress.com
Co-stimulatory tumor necrosis factor receptors (TNFRs) can sculpt the responsiveness of T
cells recognizing tumor-associated antigens. For this reason, agonist antibodies targeting …
cells recognizing tumor-associated antigens. For this reason, agonist antibodies targeting …
The formin DAAM functions as molecular effector of the planar cell polarity pathway during axonal development in Drosophila
Recent studies established that the planar cell polarity (PCP) pathway is critical for various
aspects of nervous system development and function, including axonal guidance. Although it …
aspects of nervous system development and function, including axonal guidance. Although it …
[HTML][HTML] Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM
… ), and FRL (formin-related gene in leukocytes), also exhibit similarities outside of the FH2
domain and have been termed DRL (Diaphanous-related) formins. The activity of these …
domain and have been termed DRL (Diaphanous-related) formins. The activity of these …
Inhibitory effect of individual or combinations of broadly neutralizing antibodies and antiviral reagents against cell-free and cell-to-cell HIV-1 transmission
RB Gombos, D Kolodkin-Gal, L Eslamizar… - Journal of …, 2015 - Am Soc Microbiol
To date, most therapeutic and vaccine candidates for human immunodeficiency virus type 1
(HIV-1) are evaluated preclinically for efficacy against cell-free viral challenges. However, …
(HIV-1) are evaluated preclinically for efficacy against cell-free viral challenges. However, …
[HTML][HTML] Dissecting Regulatory Networks of Filopodia Formation in a Drosophila Growth Cone Model
F-actin networks are important structural determinants of cell shape and morphogenesis.
They are regulated through a number of actin-binding proteins. The function of many of these …
They are regulated through a number of actin-binding proteins. The function of many of these …
[HTML][HTML] Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody
RB Gombos, A Gonzalez, M Manrique, D Chand… - PLoS …, 2018 - journals.plos.org
CTLA-4 and CD28 exemplify a co-inhibitory and co-stimulatory signaling axis that dynamically
sculpts the interaction of antigen-specific T cells with antigen-presenting cells. Anti-CTLA-…
sculpts the interaction of antigen-specific T cells with antigen-presenting cells. Anti-CTLA-…