User profiles for R. Mandel

ron mandel

- Verified email at ufl.edu - Cited by 18701

Ruth Mandel

- Verified email at ucl.ac.uk - Cited by 2358

Frailty: an emerging geriatric syndrome

N Ahmed, R Mandel, MJ Fain - The American journal of medicine, 2007 - Elsevier
Frailty is a new and emerging syndrome in the field of geriatrics. The study of frailty may
provide an explanation for the downward spiral of many elderly patients after an acute illness …

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in …

…, C Rosenblad, B Georgievska, C Lundberg, RJ Mandel - Brain research, 2000 - Elsevier
During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-associated
virus (AAV) or lentivirus (LV) have been developed into highly effective vehicles for …

Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the …

PR Lowenstein, RJ Mandel, W Xiong… - Current gene …, 2007 - ingentaconnect.com
Researchers have conducted numerous pre-clinical and clinical gene transfer studies using
recombinant viral vectors derived from a wide range of pathogenic viruses such as …

A third-generation lentivirus vector with a conditional packaging system

T Dull, R Zufferey, M Kelly, RJ Mandel… - Journal of …, 1998 - Am Soc Microbiol
Vectors derived from human immunodeficiency virus (HIV) are highly efficient vehicles for in
vivo gene delivery. However, their biosafety is of major concern. Here we exploit the …

Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery

R Zufferey, T Dull, RJ Mandel, A Bukovsky… - Journal of …, 1998 - Am Soc Microbiol
In vivo transduction of nondividing cells by human immunodeficiency virus type 1 (HIV-1)-based
vectors results in transgene expression that is stable over several months. However, the …

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

R Zufferey, D Nagy, RJ Mandel, L Naldini… - Nature …, 1997 - nature.com
Retroviral vectors derived from lentiviruses such as HIV-1 are promising tools for human gene
therapy because they mediate the in vivo delivery and long-term expression of transgenes …

Nucleus basalis and thalamic control of neocortical activity in the freely moving rat

…, G Ponomareff, LJ Thal, R Mandel… - Journal of …, 1988 - Soc Neuroscience
EEG and single-unit techniques have been used to study the EEG correlates of cellular
firing in the neocortex, n. reticularis (RT) and “specific” thalamic nuclei, and the cholinergic …

[HTML][HTML] Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to …

…, P Williams, S Zolotukhin, PJ Reier, RJ Mandel… - Molecular Therapy, 2004 - cell.com
Recombinant adeno-associated virus 2 (rAAV2) has been shown to deliver genes to neurons
effectively in the brain, retina, and spinal cord. The characterization of new AAV serotypes …

Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system

…, TE Johansen, N Muzyczka, RJ Mandel… - Journal of …, 2002 - Soc Neuroscience
Recombinant adeno-associated viral vectors display efficient tropism for transduction of the
dopamine neurons of the substantia nigra. Taking advantage of this unique property of …

[BOOK][B] Cosmopolitan anxieties: Turkish challenges to citizenship and belonging in Germany

R Mandel - 2008 - books.google.com
Mandel examines the tensions in Germany between race-… Mandel explains that within
Germany the popular understanding … Mandel analyzes how representations of Turkish difference …