Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

…, S Higman, S Pang, RA Waniewski - Journal of …, 1990 - Soc Neuroscience
Swelling of primary astrocyte cultures by exposing them to hypotonic media caused release
of label after the cells had been allowed to accumulate 3H-L-glutamate, 3H-D-aspartate, or …

Preferential utilization of acetate by astrocytes is attributable to transport

RA Waniewski, DL Martin - Journal of Neuroscience, 1998 - Soc Neuroscience
Exogenous acetate is preferentially metabolized by astrocytes in the CNS, but the biochemical
basis for this selectivity is unknown. We observed that rat cortical astrocytes produce 14 …

Exogenous glutamate is metabolized to glutamine and exported by rat primary astrocyte cultures

RA Waniewski, DL Martin - Journal of neurochemistry, 1986 - Wiley Online Library
Waniewski R. A. and Martin DL Exogenous glutamate is metabolized to glutamine and …
The uptake of glutamate was examined as previously described by Waniewski and Martin (1984). …

Physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures

RA Waniewski - Journal of neurochemistry, 1992 - Wiley Online Library
Waniewski R. A. Physiological levels of ammonia regulate glutamine synthesis from … A
comparison of the present results to our earlier findings with 9 pM glutamate (Waniewski and …

Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx

RA Waniewski, DL Martin - Journal of Neuroscience, 1984 - Soc Neuroscience
… inhibition is selective for glia over neurons (Waniewski and Martin, 1983). Ethacrynic acid
and DIDS had no such glia-specific action (RA Waniewski and DL Martin, unpublished data). …

Astrocytes and synaptosomes transport and metabolize lactate and acetate differently

RA Waniewski, DL Martin - Neurochemical research, 2004 - Springer
… The data for acetate were taken from Waniewski and Martin (6). ND, not detectable; NS, not
saturable; TR, too rapid to … The data for acetate were taken from Waniewski and Martin (6). …

Analysis of aspartate and glutamate in human cerebrospinal fluid by high-performance liquid chromatography with automated precolumn derivatization

DC Spink, JW Swann, OC Snead, RA Waniewski… - Analytical …, 1986 - Elsevier
A method is described for the analysis of the neuroexcitatory amino acids, aspartate and
glutamate, in human cerebrospinal fluid (CSF) by reverse-phase, high-performance liquid …

Astrocytic swelling in traumatic-hypoxic brain injury: Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells

…, JW Rose, KD Barron, RA Waniewski… - Molecular and Chemical …, 1989 - Springer
… However, SITS also inhibits glial high affinity, Na'-dependent uptake of L-glutamic acid (Waniewski
and Martin, 1983), and, as we have shown in this chapter, L-644,711 also has this …

Alterations in γ-aminobutyric acid content in the rat superior cervical ganglion and pineal gland

RA Waniewski, A Suria - Life Sciences, 1977 - Elsevier
The endogenous γ-aminobutyric acid (GABA) content of the rat pineal gland and superior
cervical ganglion (SCG) was measured by high pressure liquid chromatography. It was found …

Post-mortem degradation of brain glutamate decarboxylase

SB Martin, RA Waniewski, G Battaglioli… - Neurochemistry …, 2003 - Elsevier
The post-mortem stability of the GABA synthesizing enzyme glutamate decarboxylase (GAD)
was studied by using SDS–PAGE and quantitative immunoblotting to measure the rates of …