User profiles for S. B. Oh
Seog Bae OhSeoul National University Verified email at snu.ac.kr Cited by 9544 |
Cellular and molecular mechanisms of dental nociception
Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms.
Here we review recent advances in our understanding of inflammatory tooth pain and …
Here we review recent advances in our understanding of inflammatory tooth pain and …
Role of TRP channels in pain sensation
… results from the GlaxoSmithKline developed-compound SB-705498 have shown potential
therapeutic efficacy as a TRPV1 antagonist drug. SB-705498 significantly reduced capsaicin-…
therapeutic efficacy as a TRPV1 antagonist drug. SB-705498 significantly reduced capsaicin-…
Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons
Human immunodeficiency virus-1 (HIV-1) infection is associated with numerous effects on
the nervous system, including pain and peripheral neuropathies. We now demonstrate that …
the nervous system, including pain and peripheral neuropathies. We now demonstrate that …
[HTML][HTML] Cytotoxic immunity in peripheral nerve injury and pain
Cytotoxicity and consequent cell death pathways are a critical component of the immune
response to infection, disease or injury. While numerous examples of inflammation causing …
response to infection, disease or injury. While numerous examples of inflammation causing …
[HTML][HTML] A critical role of toll-like receptor 2 in nerve injury-induced spinal cord glial cell activation and pain hypersensitivity
… Mice were anesthetized with halothane (2–4%) in O 2 during surgery via a nose cone. The
… The floating sections were incubated with 3% H 2 O 2 for 30 min and blocked in solution …
… The floating sections were incubated with 3% H 2 O 2 for 30 min and blocked in solution …
Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade
… DRGs were digested at 37 C in a humidified O 2 incubator for 120 min with collagenase
Type II (Worthington, 285 units/mg, 12 mg/ml final concentration) and dispase II (Roche, 1 unit/…
Type II (Worthington, 285 units/mg, 12 mg/ml final concentration) and dispase II (Roche, 1 unit/…
Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury
Glial activation is known to contribute to pain hypersensitivity following spinal sensory nerve
injury. In this study, we investigated mechanisms by which glial cell activation in medullary …
injury. In this study, we investigated mechanisms by which glial cell activation in medullary …
Activation of vanilloid receptor 1 (VR1) by eugenol
The structural similarity of eugenol with capsaicin suggests that these two agents may share
molecular mechanisms to produce their effects. We investigated the effects of eugenol in …
molecular mechanisms to produce their effects. We investigated the effects of eugenol in …
TLR3‐mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3‐induced IP‐10 …
Viral infection is one of the leading causes of brain encephalitis and meningitis. Recently, it
was reported that Toll‐like receptor‐3 (TLR3) induces a double‐stranded RNA (dsRNA)‐…
was reported that Toll‐like receptor‐3 (TLR3) induces a double‐stranded RNA (dsRNA)‐…
[PDF][PDF] TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord
Neuropathic pain and allodynia may arise from sensitization of central circuits. We report a
mechanism of disinhibition-based central sensitization resulting from long-term depression (…
mechanism of disinhibition-based central sensitization resulting from long-term depression (…