HIV superinfection
Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002.
Superinfection is defined as the reinfection of an individual who already has an established …
Superinfection is defined as the reinfection of an individual who already has an established …
[HTML][HTML] Phase 3 safety and efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 vaccine
…, E DeJesus, M Hassman, SJ Little… - … England Journal of …, 2021 - Mass Medical Soc
Background The safety and efficacy of the AZD1222 (ChAdOx1 nCoV-19) vaccine in a large,
diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (…
diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (…
Rapid evolution of the neutralizing antibody response to HIV type 1 infection
DD Richman, T Wrin, SJ Little… - Proceedings of the …, 2003 - National Acad Sciences
… This assay consistently generates neutralization curves similar in shape and slope and with
little variability in duplicate assay wells (Fig. 2). As a result, IC 50 titers (1/dilution that confers …
little variability in duplicate assay wells (Fig. 2). As a result, IC 50 titers (1/dilution that confers …
[HTML][HTML] Antiretroviral-drug resistance among patients recently infected with HIV
Background Among persons in North America who are newly infected with the human
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs has …
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs has …
The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response
RH Haubrich, SJ Little, JS Currier, DN Forthal… - Aids, 1999 - journals.lww.com
… a,b ; Little, Susan J. a ; Currier, Judith S. d ; Forthal, Donald N. … A question regarding the
patient‚s satisfaction with the primary provider was categorized using a 6 point scale from little (<…
patient‚s satisfaction with the primary provider was categorized using a 6 point scale from little (<…
[HTML][HTML] Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy
Background The relationship between the timing of the initiation of antiretroviral therapy (ART)
after infection with human immunodeficiency virus type 1 (HIV-1) and the recovery of CD4…
after infection with human immunodeficiency virus type 1 (HIV-1) and the recovery of CD4…
Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of pavlovian approach …
Stimuli paired with primary rewards can acquire emotional valence and the ability to elicit
automatic, Pavlovian approach responses that have been shown to be mediated by the …
automatic, Pavlovian approach responses that have been shown to be mediated by the …
Viral dynamics of acute HIV-1 infection
… SJ Little. For individuals unable to identify a single high-risk exposure, the range of potential
exposure dates was recorded and the midpoint in this range was assigned as the HIV …
exposure dates was recorded and the midpoint in this range was assigned as the HIV …
Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1
Patients in whom virologic suppression is achieved with highly active antiretroviral therapy (HAART)
retain long-lived cellular reservoirs of human immunodeficiency virus type 1 (HIV-1); …
retain long-lived cellular reservoirs of human immunodeficiency virus type 1 (HIV-1); …
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection
…, CJ Petropoulos, SJ Little… - Proceedings of the …, 2005 - National Acad Sciences
HIV type 1 (HIV-1) can rapidly escape from neutralizing antibody responses. The genetic
basis of this escape in vivo is poorly understood. We compared the pattern of evolution of the …
basis of this escape in vivo is poorly understood. We compared the pattern of evolution of the …