User profiles for V. Bracchi-Ricard

Valerie Bracchi-Ricard

Assistant Research Professor of Biology, Drexel University
Verified email at drexel.edu
Cited by 2260

Inhibition of astroglial nuclear factor κB reduces inflammation and improves functional recovery after spinal cord injury

R Brambilla, V Bracchi-Ricard, WH Hu… - The Journal of …, 2005 - rupress.org
In the central nervous system (CNS), the transcription factor nuclear factor (NF)-κB is a key
regulator of inflammation and secondary injury processes. After trauma or disease, the …

[HTML][HTML] NIBP, a novel NIK and IKKβ-binding protein that enhances NF-κB activation

…, XM Mo, R Brambilla, V Bracchi-Ricard… - Journal of Biological …, 2005 - ASBMB
The transcription factor NF-κB plays an important role in both physiological and pathological
events in the central nervous system. Nevertheless, the mechanisms of NF-κB-mediated …

Nuclear factor kappa B signaling initiates early differentiation of neural stem cells

…, J Liu, S Yao, F Li, L Xin, M Lai, V BracchiRicard… - Stem …, 2012 - academic.oup.com
Inflammatory mediators, many of which activate the signaling of nuclear factor kappa B (NFκB),
have received increasing attention in the field of neurogenesis. NFκB signaling regulates …

[HTML][HTML] Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

HG Novrup, V Bracchi-Ricard, DG Ellman… - Journal of …, 2014 - Springer
Background Glial cell activation and overproduction of inflammatory mediators in the central
nervous system (CNS) have been implicated in acute traumatic injuries to the CNS, …

Prior regular exercise improves clinical outcome and reduces demyelination and axonal injury in experimental autoimmune encephalomyelitis

…, R Brambilla, V BracchiRicard… - Journal of …, 2016 - Wiley Online Library
Although previous studies have shown that forced exercise modulates inflammation and is
therapeutic acutely for experimental autoimmune encephalomyelitis ( EAE ), the long‐term …

Soluble TNFα signaling within the spinal cord contributes to the development of autonomic dysreflexia and ensuing vascular and immune dysfunction after spinal cord …

…, P Osei-Owusu, V Bracchi-Ricard… - Journal of …, 2018 - Soc Neuroscience
Cardiovascular disease and susceptibility to infection are leading causes of morbidity and
mortality for individuals with spinal cord injury (SCI). A major contributor to these is autonomic …

TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes

…, GF Martinez, V Bracchi-Ricard… - Proceedings of the …, 2019 - National Acad Sciences
Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that is linked to
immune modulation and tissue regeneration. Here, we show that TNFR2 essentially promotes …

PfPK6, a novel cyclin-dependent kinase/mitogen-activated protein kinase-related protein kinase from Plasmodium falciparum

V Bracchi-Ricard, S Barik, C DELVECCHIO… - Biochemical …, 2000 - portlandpress.com
We have isolated a novel protein kinase cDNA, PfPK6, by differential display RT-PCR (DDRT-PCR)
of mRNA obtained from different asexual erythrocytic stages of Plasmodium …

[HTML][HTML] Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression

J Zha, A Smith, S Andreansky, V Bracchi-Ricard… - Journal of …, 2014 - Springer
Background Chronic spinal cord injury (SCI) induces immune depression in patients, which
contributes to their higher risk of developing infections. While defects in humoral immunity …

Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis

R Fischer, T Padutsch, V Bracchi-Ricard… - Brain, behavior, and …, 2019 - Elsevier
Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that promotes immune
modulation and tissue regeneration and is recognized as a potential therapeutic target for …