User profiles for V. Bracchi-Ricard
Valerie Bracchi-RicardAssistant Research Professor of Biology, Drexel University Verified email at drexel.edu Cited by 2260 |
Inhibition of astroglial nuclear factor κB reduces inflammation and improves functional recovery after spinal cord injury
In the central nervous system (CNS), the transcription factor nuclear factor (NF)-κB is a key
regulator of inflammation and secondary injury processes. After trauma or disease, the …
regulator of inflammation and secondary injury processes. After trauma or disease, the …
[HTML][HTML] NIBP, a novel NIK and IKKβ-binding protein that enhances NF-κB activation
…, XM Mo, R Brambilla, V Bracchi-Ricard… - Journal of Biological …, 2005 - ASBMB
The transcription factor NF-κB plays an important role in both physiological and pathological
events in the central nervous system. Nevertheless, the mechanisms of NF-κB-mediated …
events in the central nervous system. Nevertheless, the mechanisms of NF-κB-mediated …
Nuclear factor kappa B signaling initiates early differentiation of neural stem cells
…, J Liu, S Yao, F Li, L Xin, M Lai, V Bracchi‐Ricard… - Stem …, 2012 - academic.oup.com
Inflammatory mediators, many of which activate the signaling of nuclear factor kappa B (NFκB),
have received increasing attention in the field of neurogenesis. NFκB signaling regulates …
have received increasing attention in the field of neurogenesis. NFκB signaling regulates …
[HTML][HTML] Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice
HG Novrup, V Bracchi-Ricard, DG Ellman… - Journal of …, 2014 - Springer
Background Glial cell activation and overproduction of inflammatory mediators in the central
nervous system (CNS) have been implicated in acute traumatic injuries to the CNS, …
nervous system (CNS) have been implicated in acute traumatic injuries to the CNS, …
Prior regular exercise improves clinical outcome and reduces demyelination and axonal injury in experimental autoimmune encephalomyelitis
…, R Brambilla, V Bracchi‐Ricard… - Journal of …, 2016 - Wiley Online Library
Although previous studies have shown that forced exercise modulates inflammation and is
therapeutic acutely for experimental autoimmune encephalomyelitis ( EAE ), the long‐term …
therapeutic acutely for experimental autoimmune encephalomyelitis ( EAE ), the long‐term …
Soluble TNFα signaling within the spinal cord contributes to the development of autonomic dysreflexia and ensuing vascular and immune dysfunction after spinal cord …
…, P Osei-Owusu, V Bracchi-Ricard… - Journal of …, 2018 - Soc Neuroscience
Cardiovascular disease and susceptibility to infection are leading causes of morbidity and
mortality for individuals with spinal cord injury (SCI). A major contributor to these is autonomic …
mortality for individuals with spinal cord injury (SCI). A major contributor to these is autonomic …
TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes
…, GF Martinez, V Bracchi-Ricard… - Proceedings of the …, 2019 - National Acad Sciences
Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that is linked to
immune modulation and tissue regeneration. Here, we show that TNFR2 essentially promotes …
immune modulation and tissue regeneration. Here, we show that TNFR2 essentially promotes …
PfPK6, a novel cyclin-dependent kinase/mitogen-activated protein kinase-related protein kinase from Plasmodium falciparum
V Bracchi-Ricard, S Barik, C DELVECCHIO… - Biochemical …, 2000 - portlandpress.com
We have isolated a novel protein kinase cDNA, PfPK6, by differential display RT-PCR (DDRT-PCR)
of mRNA obtained from different asexual erythrocytic stages of Plasmodium …
of mRNA obtained from different asexual erythrocytic stages of Plasmodium …
[HTML][HTML] Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression
J Zha, A Smith, S Andreansky, V Bracchi-Ricard… - Journal of …, 2014 - Springer
Background Chronic spinal cord injury (SCI) induces immune depression in patients, which
contributes to their higher risk of developing infections. While defects in humoral immunity …
contributes to their higher risk of developing infections. While defects in humoral immunity …
Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis
R Fischer, T Padutsch, V Bracchi-Ricard… - Brain, behavior, and …, 2019 - Elsevier
Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that promotes immune
modulation and tissue regeneration and is recognized as a potential therapeutic target for …
modulation and tissue regeneration and is recognized as a potential therapeutic target for …