[HTML][HTML] Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

AC Sedgwick, L Wu, HH Han, SD Bull, XP He… - Chemical Society …, 2018 - pubs.rsc.org
he undertook an industrial placement at BioFocus (now Charles River) working as a medicinal
chemist. HeHe carried out his postdoctoral research with Professor Kaixian Chen (SIMM, …

[HTML][HTML] Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

…, BP Emery, AC Sedgwick, SD Bull, XP He… - Chemical Society …, 2020 - pubs.rsc.org
… In 2017 he began his PhD in synthetic organic chemistry under the supervision of Prof.
Steven D. Bull. … In 2011, he was selected as a member of the Chinese Academy of Science. …

[HTML][HTML] The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

…, L Wu, Y Zang, AC Sedgwick, J Li, XP He… - Chemical Society …, 2023 - pubs.rsc.org
He received his PhD in 2020 from ECUST under the supervision of Prof. Xiao-Peng He.
His research interests include fluorescent probes for disease theranostic applications and …

[HTML][HTML] Small-molecule fluorescence-based probes for interrogating major organ diseases

…, AC Sedgwick, J Li, JL Sessler, XP He… - Chemical Society …, 2021 - pubs.rsc.org
… From 2019 he has served as the director of SIMM. … After postdoctoral stays in Strasbourg
and Kyoto, he accepted a position at the University of Texas at Austin, where he is currently the …

Reaction-based fluorescent probes for the detection and imaging of reactive oxygen, nitrogen, and sulfur species

…, AC Sedgwick, X Sun, SD Bull, XP He… - Accounts of chemical …, 2019 - ACS Publications
Conspectus This Account describes a range of strategies for the development of fluorescent
probes for detecting reactive oxygen species (ROS), reactive nitrogen species (RNS), and …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
He is pursuing his PhD degree in applied chemistry under the supervision of Prof. He
Tian. His current research interests are focused on the construction of fluorescent probes and …

[PDF][PDF] Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model

XP He, R Kotloski, S Nef, BW Luikart, LF Parada… - Neuron, 2004 - cell.com
Epileptogenesis is the process whereby a normal brain becomes epileptic. We hypothesized
that the neurotrophin brain-derived neurotrophic factor (BDNF) activates its receptor, TrkB, …

Fluorescent probes for the detection of disease-associated biomarkers

…, Y Zang, XR Yang, J Yoon, TD James, J Li, XP He - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

Transition metal chelators, pro-chelators, and ionophores as small molecule cancer chemotherapeutic agents

…, DM Knoll, GI Vargas-Zúńiga, XP He… - Chemical Society …, 2020 - pubs.rsc.org
He finished his MSc in Chemistry in 2016, and his PhD thesis in 2019, both from KIT. Currently,
he is a postdoctoral research fellow at the University of Texas at Austin working under the …

Dual-channel fluorescent probe for the simultaneous monitoring of peroxynitrite and adenosine-5′-triphosphate in cellular applications

…, H Zhang, C Huang, Y Zang, J Li, XP He… - Journal of the …, 2021 - ACS Publications
Changes in adenosine triphosphate (ATP) and peroxynitrite (ONOO – ) concentrations have
been correlated in a number of diseases including ischemia-reperfusion injury and drug-…