Early-life stimulation (eg brief handling) attenuates the behavioral and neuroendocrine
responses to stressors encountered in adulthood, particularly with respect to activation of …

Stressful events promote neurochemical changes that may be involved in the provocation of
depressive disorder. In addition to neuroendocrine substrates (eg corticotropin releasing …

… Lacosta S, Merali Z, Anisman H. Central monoamine … Anisman H, Kokkinidis L, Merali Z.
InŻuence of interleukin 2 … Anisman H, Ravindran AV, GrifŽths J, Merali Z. Endocrine and cytokine …

Corticotropin-releasing hormone (CRH) and GABA have been implicated in depression,
and there is reason to believe that GABA may influence CRH functioning. The levels of CRH, …

Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …

BACKGROUND: Epigenetic mechanisms may be involved in the reprogramming of gene
expression in response to stressful stimuli. This investigation determined whether epigenetic …

Depression has been associated with both suppression and enhancement of various
aspects of immune functioning. It was of interest to determine whether cytokine alterations …

Anatomical studies have established the existence of reciprocal relationships between the
main population of monoamine, serotonin (5-HT), norepinephrine (NE) and dopamine (DA) …

Environmental enrichment (EE) has beneficial neurobiological, physiological and behavioral
effects. The purpose of the present paper is to review the animal research literature …

The molecular mechanisms mediating degeneration of midbrain dopamine neurons in
Parkinson's disease (PD) are poorly understood. Here, we provide evidence to support a role for …