Current theories suggest that bone modeling and remodeling are controlled at the cellular
level through signals mediated by osteocytes. However, the specific signals to which bone …

Currently, 65% of Americans are overweight, which leads to well-supported cardiovascular
and cognitive declines. Little, however, is known concerning obesity's impact on sensory …

On the basis of these 2 large controlled trials, along with smaller studies and numerous
epidemiological reports, the consistent findings related to microvascular risk reduction with …

It is often assumed that there is little or no sex bias within either Type I (insulin-dependent) or
Type II (non-insulin-dependent) diabetes mellitus. This review considers evidence that sex …

Rapid demographic, sociocultural, and economic transitions are driving increases in the risk
and prevalence of diabetes and other non-communicable diseases (NCDs) in sub-Saharan …

The incidence of childhood type 1 diabetes increased worldwide in the closing decades of
the 20th century, but the origins of this increase are poorly documented. A search through the …

Strategies for assessing risk of progression to IDDM, based on single and combined autoantibody
measurement, were evaluated in 2,855 schoolchildren (median age 11.4 years) and …

Background Results of studies in animals and human beings suggest that type 1 diabetes is
preventable. Nicotinamide prevents autoimmune diabetes in animal models, possibly …

OBJECTIVE Type 2 diabetes is associated with an increased risk of several types of cancer
and with reduced survival after cancer diagnosis. We examined the hypotheses that survival …

The incidence of childhood type 1 diabetes has risen over the past 50 years. We compared
the frequency of HLA class II haplotypes in 194 patients diagnosed more than 50 years ago …