Sedation and anesthesia mediated by distinct GABAA receptor isoforms
…, J Myers, C Sur, O Howell, AR Rutter… - Journal of …, 2003 - Soc Neuroscience
The specific mechanisms underlying general anesthesia are primarily unknown. The intravenous
general anesthetic etomidate acts by potentiating GABA A receptors, with selectivity for …
general anesthetic etomidate acts by potentiating GABA A receptors, with selectivity for …
Discovery of GSK2795039, a novel small molecule NADPH oxidase 2 inhibitor
…, DW Chen, V Jaquet, AR Rutter - Antioxidants & redox …, 2015 - liebertpub.com
Aims: The NADPH oxidase (NOX) family of enzymes catalyzes the formation of reactive
oxygen species (ROS). NOX enzymes not only have a key role in a variety of physiological …
oxygen species (ROS). NOX enzymes not only have a key role in a variety of physiological …
[HTML][HTML] Evolutionary and biomechanical basis of drumming behavior in woodpeckers
ER Schuppe, AR Rutter, TJ Roberts… - Frontiers in Ecology and …, 2021 - frontiersin.org
… ES and AR contributed to the writing of the manuscript and the synthesis of its ideas. TR and
MF contributed to the writing of the manuscript, establishing the manuscript main points and …
MF contributed to the writing of the manuscript, establishing the manuscript main points and …
Evidence from gene knockout studies implicates Asc‐1 as the primary transporter mediating d‐serine reuptake in the mouse CNS
AR Rutter, RL Fradley, EM Garrett… - European Journal of …, 2007 - Wiley Online Library
In the mammalian central nervous system, transporter‐mediated reuptake may be critical for
terminating the neurotransmitter action of d‐serine at the strychnine insensitive glycine site …
terminating the neurotransmitter action of d‐serine at the strychnine insensitive glycine site …
Behavioral and biochemical characterization of a mutant mouse strain lacking D-amino acid oxidase activity and its implications for schizophrenia
…, EJ Armstrong, RB Heavens, AR Rutter… - Molecular and Cellular …, 2006 - Elsevier
d-Amino acid oxidase (DAO) degrades d-serine, a co-agonist at the NMDA receptor (NMDAR).
Hypofunction of the NMDAR has been suggested to contribute to the pathophysiology of …
Hypofunction of the NMDAR has been suggested to contribute to the pathophysiology of …
Heteromerization and colocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia
AR Rutter, QP Ma, M Leveridge, TP Bonnert - Neuroreport, 2005 - journals.lww.com
Coassociation of the vanilloid transient receptor potential (Trp) ion channels, TrpV1 and
TrpV2, was investigated by immunoprecipitation and immunofluorescence in transfected …
TrpV2, was investigated by immunoprecipitation and immunofluorescence in transfected …
Differential interaction of NMDA receptor subtypes with the post‐synaptic density‐95 family of membrane associated guanylate kinase proteins
SL Cousins, M Papadakis, AR Rutter… - Journal of …, 2008 - Wiley Online Library
NMDA receptors are a subclass of ionotropic glutamate receptors. They are trafficked and/or
clustered at synapses by the post‐synaptic density (PSD)‐95 membrane associated …
clustered at synapses by the post‐synaptic density (PSD)‐95 membrane associated …
Discrete expression of TRPV2 within the hypothalamo‐neurohypophysial system: Implications for regulatory activity within the hypothalamic‐pituitary‐adrenal axis
A Wainwright, AR Rutter, GR Seabrook… - Journal of …, 2004 - Wiley Online Library
Transient receptor potential channel proteins (TRPs) constitute a steadily growing family of
ion channels with a range of purported functions. It has been demonstrated that TRPV2 is …
ion channels with a range of purported functions. It has been demonstrated that TRPV2 is …
GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side …
AR Rutter, A Poffe, P Cavallini, TG Davis… - … of Pharmacology and …, 2014 - ASPET
Small molecule phosphodiesterase (PDE) 4 inhibitors have long been known to show
therapeutic benefit in various preclinical models of psychiatric and neurologic diseases because …
therapeutic benefit in various preclinical models of psychiatric and neurologic diseases because …
Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease
K Hirano, TM Piers, KL Searle, ND Miller, AR Rutter… - Life sciences, 2009 - Elsevier
AIMS: 5-HT 6 receptor subtype is predominantly expressed in the brain, and preclinical
evidence suggests its potential role in the cognitive function. Brain microdialysis studies …
evidence suggests its potential role in the cognitive function. Brain microdialysis studies …