A growing body of literature suggests that there is a link between periodontitis and systemic
diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal …

Canonical roles for macrophages in mediating the fibrotic response after a heart attack
include extracellular matrix turnover and activation of cardiac fibroblasts to initiate collagen …

We report a multifunctional gene-trapping approach, which generates full-length Citrine fusions
with endogenous proteins and conditional mutants from a single integration event of the …

The list of factors that participate in the DNA damage response to maintain genomic stability
has expanded significantly to include a role for proteins involved in RNA processing. Here, …

Background Besides its influence on survival, growth, proliferation, invasion and metastasis,
cancer cell metabolism also greatly influences the cellular responses to molecular-targeted …

Colon cancer is a clinically diverse disease. This heterogeneity makes it difficult to determine
which patients will benefit most from adjuvant therapy and impedes the development of …

Rationale: Procoagulant microparticles constitute valuable hallmarks of cell damage.
Microparticles also behave as cellular effectors. Objectives: We hypothesized that the extent of the …

To investigate immune escape during breast tumor progression, we analyzed the composition
of leukocytes in normal breast tissues, ductal carcinoma in situ (DCIS), and invasive …

Enceladus's gravity and shape have been explained in terms of a thick isostatic ice shell
floating on a global ocean, in contradiction of the thin shell implied by librations. Here we …

The intense plume activity at the South Pole of Enceladus together with the recent detection
of libration hints at an internal water ocean underneath the outer ice shell. However, the …