Newborn screening for Krabbe disease: the New York State model

…, LE Helton, EH Kolodny, BE Kosofsky… - Pediatric …, 2009 - Elsevier
Krabbe disease is a rare inherited neurologic disorder affecting the central and peripheral
nervous systems. The disease has four phenotypes: early infantile, later onset, adolescent, …

Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation

JB Mandeville, JJA Marota, BE Kosofsky… - Magnetic resonance …, 1998 - Wiley Online Library
Dynamic measurements of regional changes in cerebral blood volume (CBV) were performed
in rat models of hypercarbia and focal neuronal activation using T 2 ‐weighted imaging …

The serotoninergic innervation of cerebral cortex: different classes of axon terminals arise from dorsal and median raphe nuclei

BE Kosofsky, ME Molliver - Synapse, 1987 - Wiley Online Library
The objective of the present study was to characterize the morphology of serotoninergic axons
in cerebral cortex of the rat and to determine whether dissimilar axon terminals arise from …

Does drug abuse beget drug abuse? Behavioral analysis of addiction liability in animal models of prenatal drug exposure

CJ Malanga, BE Kosofsky - Developmental Brain Research, 2003 - Elsevier
Prenatal exposure to drugs of abuse is the single largest preventable cause of developmental
compromise of American children today. In the clinical population, it is difficult to …

Wallerian degeneration after cerebral infarction: evaluation with sequential MR imaging.

MJ Kuhn, DJ Mikulis, DM Ayoub, BE Kosofsky… - Radiology, 1989 - pubs.rsna.org
The dynamic signal intensity changes at magnetic resonance (MR) imaging in active and
chronic wallerian degeneration in the corticospinal tract were evaluated. Forty-three patients …

Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine.

TV Nguyen, BE Kosofsky, R Birnbaum… - Proceedings of the …, 1992 - National Acad Sciences
Antipsychotic drugs are monoamine receptor antagonists. However, the mechanisms by
which these direct actions are translated into therapeutic effects are unknown. Candidate …

[HTML][HTML] Markers of celiac disease and gluten sensitivity in children with autism

…, D Hellberg, M Ajamian, CZ Tan, BE Kosofsky… - PloS one, 2013 - journals.plos.org
Objective Gastrointestinal symptoms are a common feature in children with autism, drawing
attention to a potential association with celiac disease or gluten sensitivity. However, studies …

Mechanisms of action of drugs of abuse on the developing fetal brain

CJ Malanga III, BE Kosofsky - Clinics in perinatology, 1999 - Elsevier
The consequences of public health of the acquisition and use of drugs of abuse have been
well demonstrated. Despite intense effort, however, progress has been slow in recent years …

Cocaine activation discriminates dopaminergic projections by temporal response: an fMRI study in rat

…, RM Weisskoff, MA Moskowitz, BR Rosen, BE Kosofsky - Neuroimage, 2000 - Elsevier
We applied a sensitive new functional magnetic resonance imaging technique to identify the
pattern and determinants of cocaine-induced brain activation in drug-naive rats. At doses …

BDNF-induced white matter neuroprotection and stage-dependent neuronal survival following a neonatal excitotoxic challenge

…, AP Bemelmans, P Sachs, J Mallet, BE Kosofsky… - Cerebral …, 2005 - academic.oup.com
Excitotoxicity may be critical in the formation of brain lesions associated with cerebral palsy.
When injected into the murine neopallium at postnatal day (P) 5, ibotenate (activating NMDA …