Metabolomics is the study of metabolism at the global level. This rapidly developing new
discipline has important potential implications for pharmacologic science. The concept that …

Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become
methods of choice to characterize the human metabolome and MS-based metabolomics is …

Glutathione is a storage form of cysteine and protects against reactive oxygen species and
potentially toxic xenobiotics in the central nervous system. Marked reductions in intracellular …

Context Secondary analyses of 2 randomized controlled trials and supportive epidemiologic
and preclinical data indicated the potential of selenium and vitamin E for preventing …

Minocycline mediates neuroprotection in experimental models of neurodegeneration. It
inhibits the activity 1 , 2 , 3 , 4 , 5 , 6 of caspase-1, caspase-3, inducible form of nitric oxide …

Background: Preclinical and observational studies suggest a relationship between dietary
fat intake and breast cancer, but the association remains controversial. We carried out a …

BACKGROUND: There is extensive and consistent evidence that high fruit and vegetable
intakes are associated with decreased risks of many cancers, but results for prostate cancer …

PURPOSE: The Women’s Health Initiative (WHI) is the largest research program ever
initiated in the United States with a focus on diet and health. Therefore, it is important to …

Supply networks are composed of large numbers of firms from multiple interrelated
industries. Such networks are subject to shifting strategies and objectives within a dynamic …

Adenocarcinomas of the esophagus and gastric cardia were once rare. However, for unknown
reasons, their incidence has been increasing rapidly over the past 15 years in the United …