Light scattering by brain tissue and phototoxicity are major obstacles to the use of high-resolution
optical imaging and photo-activation (‘uncaging’) of bioactive compounds from inactive …

A commonly observed neural correlate of working memory is firing that persists after the
triggering stimulus disappears. Substantial effort has been devoted to understanding the many …

Synaptic transmission between dendrites in the olfactory bulb is thought to play a major role
in the processing of olfactory information. Glutamate released from mitral cell dendrites …

Serotonin (5HT) is a critical modulator of neural circuits that support diverse behaviors and
physiological processes, and multiple lines of evidence implicate abnormal serotonergic …

Inhibition generated by granule cells, the most common GABAergic cell type in the olfactory
bulb, plays a critical role in shaping the output of the olfactory bulb. However, relatively little …

Acute, uncontrollable stress increases norepinephrine (NE) turnover in the rat's brain (thereby
depleting NE) and diminishes the animal's subsequent tendency to explore a novel …

The ipsilateral associational pathway connects different septotemporal levels of the dentate
gyrus. Neurons of the dentate hilus project hundreds of micrometers from the cells of origin …

Inhibitory local circuits in the olfactory bulb play a critical role in determining the firing patterns
of output neurons. However, little is known about the circuitry in the major plexiform layers …

The dentate hilus has been extensively studied in relation to its potential role in memory and
in temporal lobe epilepsy. Little is known, however, about the synapses formed between the …

Using two photon–guided focal stimulation, we found spike timing–dependent plasticity of
proximal excitatory inputs to olfactory bulb granule cells that originated, in part, from cortical …