The systematic translation of cancer genomic data into knowledge of tumour biology and
therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust …

Understanding how DNA binding proteins control global gene expression and chromosomal
maintenance requires knowledge of the chromosomal locations at which these proteins …

This paper summarises an ambitious research agenda aiming to uncover the factors that
affect help-seeking among young people for mental health problems. The research set out to …

How is contestation on European integration structured among national political parties? Are
issues arising from European integration assimilated into existing dimensions of domestic …

The stability of the Wnt pathway transcription factor β-catenin is tightly regulated by the multi-subunit
destruction complex. Deregulated Wnt pathway activity has been implicated in many …

An appropriate cellular response to implanted surfaces is essential for tissue regeneration
and integration. It is well described that implanted materials are immediately coated with …

Oncogenic mutations in the serine/threonine kinase B-RAF (also known as BRAF) are found
in 50–70% of malignant melanomas 1 . Pre-clinical studies have demonstrated that the B-…

Despite the high prevalence of mental health problems and disorders that develop in
adolescence and early adulthood, young people tend to not seek professional help. Young men …

The neostriatum is the larges* component of the basal ganglia, and the main recipient of
afferents to the basal ganglia from the cerebral cortex and thalamus. Studies of the cellular …

1.1 Background Dendrimers and dendrons are architectural motifs synthesized by either
divergent or convergent iterative methods, and therefore, they provide monodisperse …