Achieving therapeutic efficacy in ischemic stroke represents one of the biggest challenges in
translational neurobiology. Despite extensive efforts, tissue plasminogen activator remains …

… of the crenarchaeon Pyrodictium abyssi (a hyperthermophile that can grow up to 1108C),
the cells are inserted into a reticulated network whose function is still unknown and (C) …

… For 5, the angle between the rotational axis of the tolyl linker and the C(sp 3 )−N bond
connecting linker and cap is fixed at ∼113, forcing the carbazole to lie against the catalytic …

… (C and D) Mean neurite length measured after 24 h coculture with either R2 or R2M21+…
(D), and measured by using Metamorph (C). Significant increase in neurite length relative to …

Background Increased rates of sexually transmitted infections (STIs) have been reported
among men who have sex with men. We aimed to assess whether post-exposure prophylaxis (…

Lateral gene transfers are frequent among prokaryotes, although their detection remains
difficult. If all genes are equally affected, this questions the very existence of an organismal …

We used a phylogenetic approach to analyze the evolution of methanogenesis and
methanogens. We show that 23 vertically transmitted ribosomal proteins do not support the …

The first phyla that emerge in the tree of life based on ribosomal RNA (rRNA) sequences are
hyperthermophilic, which led to the hypothesis that the universal ancestor, and possibly the …

… Some Archaea exhibit unique features in the living world, such as methanogenesis or the
ability to grow at temperatures above 95C or at pHs as low as 0. Recently, the search for new …

Background Cultivable archaeal species are assigned to two phyla - the Crenarchaeota and
the Euryarchaeota - by a number of important genetic differences, and this ancient split is …