[HTML][HTML] TGF-β and BMP signaling in osteoblast differentiation and bone formation
… If Smad1 is modified, it can modulate BMP-mediated osteogenesis 70 and the intensity of
BMP signals can be determined by BMP receptors via Smad1 C-terminal phosphorylation 71 . …
BMP signals can be determined by BMP receptors via Smad1 C-terminal phosphorylation 71 . …
Recent progress in the biology and physiology of sirtuins
The sirtuins are a highly conserved family of NAD + -dependent enzymes that regulate lifespan
in lower organisms. Recently, the mammalian sirtuins have been connected to an ever …
in lower organisms. Recently, the mammalian sirtuins have been connected to an ever …
Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery
… 7.3 and 37 C) was greatly enhanced at pH 5.3 and 40 C (simulating … at physiological pH and
37 C but significantly accelerated at … in 48 h at pH 5.2 and 43 C due to structural collapse of …
37 C but significantly accelerated at … in 48 h at pH 5.2 and 43 C due to structural collapse of …
The reactome pathway knowledgebase 2022
…, C Sevilla, L Matthews, C Gong, C Deng… - Nucleic acids …, 2022 - academic.oup.com
… (C) Comparison of different timepoints of a longitudinal study. The time series analysis of the
JAK/SYK inhibitor effect shows earlier down-regulation of MHC signaling, followed by broad …
JAK/SYK inhibitor effect shows earlier down-regulation of MHC signaling, followed by broad …
Deep high-resolution representation learning for visual recognition
… The first stage contains 4 residual units where each unit is formed by a bottleneck with the
width 64, and is followed by one 3 Â 3 convolution changing the width of feature maps to C. …
width 64, and is followed by one 3 Â 3 convolution changing the width of feature maps to C. …
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
p21 CIP11WAF1 is a CDK Inhibitor regulated by the tumor suppressor p53 and is hypothesized
to mediate G1 arrest. p53 has been suggested to derive anti-oncogenic properties from …
to mediate G1 arrest. p53 has been suggested to derive anti-oncogenic properties from …
Superparamagnetic High-Magnetization Microspheres with an Fe3O4@SiO2 Core and Perpendicularly Aligned Mesoporous SiO2 Shell for Removal of …
… However, these materials either show poor magnetic response due to the difficulty in
increasing Fe 3 O 4 mass fraction 12a-c or possess irregular core−shell structures, 12b and they …
increasing Fe 3 O 4 mass fraction 12a-c or possess irregular core−shell structures, 12b and they …
[HTML][HTML] Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
…, R Wada, T Yamashita, Y Mi, CX Deng… - The Journal of …, 2000 - Am Soc Clin Investig
… as follows: initial denaturation at 95C for 10 minutes followed by up to 35 cycles of denaturation
at 95C (1 minute), annealing at 55C (1 minute), and extension at 72C (1 min). Amplified …
at 95C (1 minute), annealing at 55C (1 minute), and extension at 72C (1 min). Amplified …
[HTML][HTML] 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
Defective DNA repair by homologous recombination (HR) is thought to be a major contributor
to tumorigenesis in individuals carrying Brca1 mutations. Here, we show that DNA breaks …
to tumorigenesis in individuals carrying Brca1 mutations. Here, we show that DNA breaks …
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
…, J Liu, A Vassilopoulos, CX Deng… - Proceedings of the …, 2008 - National Acad Sciences
Here, we demonstrate a role for the mitochondrial NAD-dependent deacetylase Sirt3 in the
maintenance of basal ATP levels and as a regulator of mitochondrial electron transport. We …
maintenance of basal ATP levels and as a regulator of mitochondrial electron transport. We …