Background Neoadjuvant chemotherapy (NACT) for early breast cancer can make breast-conserving
surgery more feasible and might be more likely to eradicate micrometastatic …

… Grade C anastomotic leakage Patients with grade C anastomotic leakage are often quite ill
and require operative re-laparotomy. In the majority of patients and in particular in those who …

Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster,
better and less expensively than current standards. Optical imaging that exploits invisible near-…

Background Short-term preoperative radiotherapy and total mesorectal excision have each
been shown to improve local control of disease in patients with resectable rectal cancer. We …

… and RRM2), a nuclear localization signal and a glycine-rich C-terminal tail (5,6). The
glycine-rich C-terminal region is required for its exon skipping and inhibitory splicing activities and, …

Many apoptotic signaling pathways are directed to mitochondria, where they initiate the release
of apoptogenic proteins and open the proposed mitochondrial permeability transition (PT…

Background A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves
survival among patients with incurable locally advanced or metastatic gastric adenocarcinoma. …

Background Curative resection is the treatment of choice for gastric cancer, but it is unclear
whether this operation should include an extended (D2) lymph-node dissection, as …

… [V, C]. Screening for thyroid cancer should be performed by annual sonography of the
neck [V, C]. … be performed in search for desmoid tumours [V, C]. Screening for other extra-colonic …

Background If treatment of the axilla is indicated in patients with breast cancer who have a
positive sentinel node, axillary lymph node dissection is the present standard. Although …