Behavioral assessment after spinal cord contusion has long focused on open field locomotion
using modifications of a rating scale developed by Tarlov and Klinger (1954). However, on…

Injury reproducibility is an important characteristic of experimental models of spinal cord
injuries (SCI) because it limits the variability in locomotor and anatomical outcome measures. …

… The Multicenter Animal Spinal Cord Injury Study (MASCIS) adopted a modified 21-point
open field locomotor scale developed by Basso, Beattie, and Bresnahan (BBB) at Ohio State …

The most difficult clinical questions in stroke rehabilitation are “What is this patient’s
potential for recovery?” and “What is the best rehabilitation strategy for this person, given her/his …

… Basso DM. Neuroanatomical substrates of functional recovery after experimental spinal
cord injury: implications of basic science research for human spinal cord injury. …

Genetically engineered mice are used extensively to examine molecular responses to spinal
cord injury (SCI). Inherent strain differences may confound behavioral outcomes; therefore, …

Activated microglia and macrophages (CNS macrophages) have been implicated in the
secondary or “bystander” pathology (eg axon injury, demyelination) that accompanies traumatic …

Spinal cord injury (SCI) impairs sensory systems causing chronic allodynia. Mechanisms
underlying neuropathic pain have been more extensively studied following peripheral nerve …

A computer-controlled electromagnetic spinal cord injury device (ESCID) has been adapted
to develop a mouse model of spinal cord contusion injury. In the present study, we have …

… Weekly open-field behavior measured locomotor recovery using the Basso, Beattie and
Bresnahan (BBB) locomotor rating scale and the Basso Mouse Scale (BMS) locomotor rating …