The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

… sampled were much shorter than the duration of a night’s dreaming, results further support
the concept of a mnemonic deficiency in dreaming compared to waking (Pace-Schott et al. …

Sleep can be addressed across the entire hierarchy of biological organization. We discuss
neuronal-network and regional forebrain activity during sleep, and its consequences for …

Background Chronic sleep-onset insomnia is a prevalent health complaint in adults. Although
behavioral and pharmacological therapies have been shown to be effective for insomnia, …

To appreciate the neural underpinnings of sleep, it is important to view this universal
mammalian behaviour at multiple levels of its biological organization. Molecularly, the circadian …

Sleep enhances memories, particularly emotional memories. As such, it has been suggested
that sleep deprivation may reduce posttraumatic stress disorder. This presumes that …

… Pace-Schott, PhD , … Pace-Schott, PhD … Pace-Schott, PhD, Center for Sleep & Cognition,
Harvard Medical School, Department of Psychiatry, Feldberg 864, Beth Israel Deaconess Medical …

… poorer extinction recall (Pace-Schott et al., under review) and that time-of-day does not fully
explain extinction learning (Pace-Schott et al., 2009) or recall (Pace-Schott, Verga, Bennett, …

Experimental data indicate a role for the prefrontal cortex in mediating normal sleep physiology,
dreaming and sleep-deprivation phenomena. During nonrandom-eye-movement (NREM…

RECENT PET imaging and brain lesion studies in humans are integrated with new basic
research findings at the cellular level in animals to explain how the formal cognitive features of …