The blood-brain barrier (BBB) is composed of tightly bound endothelial cells (ECs) and
perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed …

Three members of the GATA family of transcription factors, GATA-4, -5, and -6, are expressed
in the developing heart. One family member, GATA-5, is restricted to the endocardium …

… in commissural neurons Commissural axons invade the motor columns Charron et al., 2003
… in commissural neurons Commissural axons invade the motor columns Charron et al., 2003 …

Heterozygous Tbx5 del/+ mice were generated to study the mechanisms by which TBX5
haploinsufficiency causes cardiac and forelimb abnormalities seen in Holt-Oram syndrome. …

… (F.Charron et al., unpublished results). Interestingly, neither GATA‐1 nor GATA‐6, which do
not transcriptionally synergize with Nkx2‐5, could be retained on the MBP–Nkx2‐5 column, …

Developing axons are guided to their targets by attractive and repulsive guidance cues. In
the embryonic spinal cord, the floor plate chemoattractant Netrin-1 is required to guide …

Axon outgrowth is the first step in the formation of neuronal connections, but the pathways
that regulate axon extension are still poorly understood. We find that mice deficient in …

The myocyte enhancer factor-2 (MEF2) proteins are MADS-box transcription factors that are
essential for differentiation of all muscle lineages but their mechanisms of action remain …

The ubiquity of the Internet connection to desktops has been both a boon to business as well
as a cause for concern for the security of digital assets that may be unknowingly exposed. …

… Tian and F. de Sauvage for discussions during early stages of the project; and T. … Ami
Okada and Frédéric Charron: These authors contributed equally to this work. … Frédéric Charron …