User profiles for F. Hyder

Fahmeed Hyder

Professor Radiology & Biomedical Imaging; Professor Biomedical Engineering; Yale …
Verified email at yale.edu
Cited by 20784

Energetic basis of brain activity: implications for neuroimaging

RG Shulman, DL Rothman, KL Behar, F Hyder - Trends in neurosciences, 2004 - cell.com
The complex activities of the brain need not distract us from the certainty that it uses energy
and performs work very efficiently. The human brain, which claims ∼2% of our body mass, is …

Neuronal–glial glucose oxidation and glutamatergic–GABAergic function

F Hyder, AB Patel, A Gjedde… - Journal of Cerebral …, 2006 - journals.sagepub.com
Prior 13 C magnetic resonance spectroscopy (MRS) experiments, which simultaneously
measured in vivo rates of total glutamate-glutamine cycling (V cyc(tot) ) and neuronal glucose …

In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function

DL Rothman, KL Behar, F Hyder… - Annual review of …, 2003 - annualreviews.org
… The significance of glucose oxidation for the net neuroenergetics during sensory stimulation
was evaluated by Hyder and coworkers using forepaw stimulation of anesthetized rats (25, …

Reduced cortical γ-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy

…, DL Rothman, KL Behar, F Hyder… - Archives of general …, 1999 - jamanetwork.com
Background Several lines of emerging evidence suggest that dysfunction of γ-aminobutyric
acid (GABA) systems is associated with major depression. However, investigation of this …

Increased cortical GABA concentrations in depressed patients receiving ECT

…, GF Mason, DL Rothman, F Hyder… - American Journal of …, 2003 - Am Psychiatric Assoc
OBJECTIVE: Reduced γ-aminobutyric acid (GABA) concentrations have been reported in
the plasma, CSF, and cortex of depressed subjects. Of interest is that ECT, one of the most …

Engineering of human brain organoids with a functional vascular-like system

…, KY Kim, P Sun, M Zhong, S Lee, P Patra, F Hyder… - Nature …, 2019 - nature.com
f, tSNE plot showing gene expression related to blood vessel formation and pericyte. Data
depicts results from 20,026 cells. g, Estimation of neurodevelopmental stage by enrichment of …

Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task.

…, A Puce, AC Nobre, G Bloch, F Hyder… - Proceedings of the …, 1994 - National Acad Sciences
… These mean f-test images retained only t values above a … AND f-test image was computed
for each subject in which the f-… were identified in the thresholded mean f-test images for each …

Dynamic mapping of the human visual cortex by high-speed magnetic resonance imaging.

…, G McCarthy, JM Ellermann, F Hyder… - Proceedings of the …, 1992 - National Acad Sciences
We report the use of high-speed magnetic resonance imaging to follow the changes in image
intensity in the human visual cortex during stimulation by a flashing checkerboard stimulus. …

Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging

RG Shulman, F Hyder… - Proceedings of the …, 2001 - National Acad Sciences
Positron-emission tomography and functional MRS imaging signals can be analyzed to
derive neurophysiological values of cerebral blood flow or volume and cerebral metabolic …

Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI

…, DL Rothman, RG Shulman, F Hyder - Proceedings of the …, 2002 - National Acad Sciences
Functional MRI (fMRI) is widely assumed to measure neuronal activity, but no satisfactory
mechanism for this linkage has been identified. Here we derived the changes in the energetic …