User profiles for G. S. Chiu
Grace S. ChiuProf, W&M VIMS; Aff Prof, VCU; Adj Prof, UWaterloo; Aff Asc Prof, UWash Verified email at vims.edu Cited by 473 |
[HTML][HTML] Mechanisms of chemotherapy-induced behavioral toxicities
EG Vichaya, GS Chiu, K Krukowski… - Frontiers in …, 2015 - frontiersin.org
While chemotherapeutic agents have yielded relative success in the treatment of cancer,
patients are often plagued with unwanted and even debilitating side-effects from the treatment …
patients are often plagued with unwanted and even debilitating side-effects from the treatment …
[HTML][HTML] The high costs of low-grade inflammation: persistent fatigue as a consequence of reduced cellular-energy availability and non-adaptive energy expenditure
TE Lacourt, EG Vichaya, GS Chiu, R Dantzer… - Frontiers in behavioral …, 2018 - frontiersin.org
Chronic or persistent fatigue is a common, debilitating symptom of several diseases. Persistent
fatigue has been associated with low-grade inflammation in several models of fatigue, …
fatigue has been associated with low-grade inflammation in several models of fatigue, …
Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice
MM Kaczmarczyk, AS Machaj, GS Chiu… - …, 2013 - Elsevier
The prevalence of childhood obesity has risen dramatically and coincident with this upsurge
is a growth in adverse childhood psychological conditions including impulsivity, depression, …
is a growth in adverse childhood psychological conditions including impulsivity, depression, …
[HTML][HTML] Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin
N Boukelmoune, GS Chiu, A Kavelaars… - Acta neuropathologica …, 2018 - Springer
Mesenchymal stem cells (MSCs) transfer healthy mitochondria to damaged acceptor cells
via actin-based intercellular structures. In this study, we tested the hypothesis that MSCs …
via actin-based intercellular structures. In this study, we tested the hypothesis that MSCs …
Pifithrin-μ prevents cisplatin-induced chemobrain by preserving neuronal mitochondrial function
GS Chiu, MA Maj, S Rizvi, R Dantzer, EG Vichaya… - Cancer research, 2017 - AACR
… 800 × g for 10 minutes at 4C. Collected supernatant 1 was centrifuged at 10,000 × g for 10
… After incubation on ice for 30 minutes, homogenates were centrifuged at 13,000 × g for 15 …
… After incubation on ice for 30 minutes, homogenates were centrifuged at 13,000 × g for 15 …
Fasting Induces an Anti‐Inflammatory Effect on the Neuroimmune System Which a High‐Fat Diet Prevents
DN Lavin, JJ Joesting, GS Chiu, ML Moon, J Meng… - …, 2011 - Wiley Online Library
The neuroimmunological and behavioral consequences of a high‐fat diet (HFD) are not well
delineated. This is especially true when short term (24 h) fasting is used as a physiologic …
delineated. This is especially true when short term (24 h) fasting is used as a physiologic …
Modulation of neuroimmunity by adenosine and its receptors: metabolism to mental illness
GS Chiu, GG Freund - Metabolism, 2014 - Elsevier
Adenosine is a pleiotropic bioactive with potent neuromodulatory properties. Due to its
ability to easily cross the blood–brain barrier, it can act as a signaling molecule between the …
ability to easily cross the blood–brain barrier, it can act as a signaling molecule between the …
The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice
ML Moon, JJ Joesting, MA Lawson, GS Chiu… - Metabolism, 2014 - Elsevier
Objectives Excess fat in the diet can impact neuropsychiatric functions by negatively affecting
cognition, mood and anxiety. We sought to show that the free fatty acid (FFA), palmitic acid, …
cognition, mood and anxiety. We sought to show that the free fatty acid (FFA), palmitic acid, …
[HTML][HTML] Nasal administration of mesenchymal stem cells restores cisplatin-induced cognitive impairment and brain damage in mice
GS Chiu, N Boukelmoune, ACA Chiang, B Peng… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… (G) CTGB + cells were also detected in the hippocampus while (H) no signal was detected
in the red channel. Therefore we can conclude that the fluorescent signals are specific and …
in the red channel. Therefore we can conclude that the fluorescent signals are specific and …
Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety
GS Chiu, PT Darmody, JP Walsh, ML Moon… - Brain, behavior, and …, 2014 - Elsevier
Anxiety is one of the most commonly reported psychiatric conditions, but its pathogenesis is
poorly understood. Ailments associated with activation of the innate immune system, …
poorly understood. Ailments associated with activation of the innate immune system, …