In vivo imaging of disease-related mitochondrial dynamics in a vertebrate model system

G Plucińska, D Paquet, A Hruscha… - Journal of …, 2012 - Soc Neuroscience
Mitochondria provide ATP, maintain calcium homeostasis, and regulate apoptosis. Neurons,
due to their size and complex geometry, are particularly dependent on the proper …

[PDF][PDF] Regulation of KIF1A-driven dense core vesicle transport: Ca2+/CaM controls DCV binding and liprin-α/TANC2 recruits DCVs to postsynaptic sites

R Stucchi, G Plucińska, JJA Hummel, EE Zahavi… - Cell reports, 2018 - cell.com
… indicate that CaM interacts with a short KIF1A fragment (691-752), in contrast to TANC2 and
liprin-a, which require the entire region (657-1105) to associate with KIF1A (Figure 2G) and …

Imaging of neuronal mitochondria in situ

G Plucińska, T Misgeld - Current opinion in neurobiology, 2016 - Elsevier
Highlights • Intravital imaging provides new insights into the behavior of neuronal mitochondria.
• Models for mitochondrial imaging in situ have been described from nematodes to mice. …

Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy

A Sliwa, G Plucinska, J Bednarczyk, K Lukasiuk - Neuroscience letters, 2012 - Elsevier
Approximately 30% of all epilepsy cases are acquired. At present there is no effective strategy
to stop epilepsy development after the precipitating insult. Recent data from experimental …

Nanoresolution real-time 3D orbital tracking for studying mitochondrial trafficking in vertebrate axons in vivo

F Wehnekamp, G Plucińska, R Thong, T Misgeld… - Elife, 2019 - elifesciences.org
10.7554/eLife.46059.001 We present the development and in vivo application of a feedback-based
tracking microscope to follow individual mitochondria in sensory neurons of …

Status epilepticus evokes prolonged increase in the expression of CCL3 and CCL4 mRNA and protein in the rat brain

A Guzik-Kornacka, A Sliwa, G Plucinska… - Acta Neurobiologiae …, 2011 - ane.pl
CCL3 and CCL4 are proinflammatory chemokines belonging to the CC family. Increase in
expression of mRNA coding for various chemokines including CCL3 and CCL4 has been …

[HTML][HTML] Epileptogenesis following kainic acid-induced status epilepticus in cyclin D2 knock-out mice with diminished adult neurogenesis

I Kondratiuk, G Plucinska, D Miszczuk, G Wozniak… - PLoS …, 2015 - journals.plos.org
The goal of this study was to determine whether a substantial decrease in adult neurogenesis
influences epileptogenesis evoked by the intra-amygdala injection of kainic acid (KA). …

Completion of neuronal remodeling prompts myelination along developing motor axon branches

M Wang, T Kleele, Y Xiao, G Plucinska… - Journal of Cell …, 2021 - rupress.org
… 3, F and G). Only in retreating branches were the pruning axons with emerging nodes
significantly thicker than their unmyelinated counterparts (Fig. 3 D), possibly due to the protective …

In vivo imaging of mitochondria in intact zebrafish larvae

D Paquet, G Plucińska, T Misgeld - Methods in enzymology, 2014 - Elsevier
Visualizing neuronal mitochondria in a living, intact mammalian organism is a challenge that
can be overcome in zebrafish larvae, which are highly accessible for optical imaging and …

[HTML][HTML] Trajectory data of antero-and retrograde movement of mitochondria in living zebrafish larvae

F Mieskes, F Wehnekamp, G Plucińska, R Thong… - Data in brief, 2020 - Elsevier
Recently, a large number of single particle tracking (SPT) approaches have been developed.
Generally, SPT techniques can be split into two groups: ex post facto approaches where …