User profiles for H. Kiem
Hans-Peter KiemFred Hutchinson Cancer Center Verified email at fredhutch.org Cited by 24716 |
International AIDS Society global scientific strategy: towards an HIV cure 2016
…, G Henderson, TJ Henrich, R Jefferys, HP Kiem… - Nature medicine, 2016 - nature.com
Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a
global population of more than 35 million people living with HIV, there is intense interest in …
global population of more than 35 million people living with HIV, there is intense interest in …
[PDF][PDF] SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
There is pressing urgency to understand the pathogenesis of the severe acute respiratory
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS-…
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS-…
[PDF][PDF] Hematopoietic-stem-cell-based gene therapy for HIV disease
Although combination antiretroviral therapy can dramatically reduce the circulating viral load
in those infected with HIV, replication-competent virus persists. To eliminate the need for …
in those infected with HIV, replication-competent virus persists. To eliminate the need for …
Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
… e–h, Frequency of arrhythmias is highest within the first 2 weeks after hESC-CM … or AIVR
for more than 18 h per 24 h period). NSAIVR, non-sustained accelerated idioventricular rhythm. …
for more than 18 h per 24 h period). NSAIVR, non-sustained accelerated idioventricular rhythm. …
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects
…, GE Georges, FC Grumet, HP Kiem… - Blood, The Journal …, 2001 - ashpublications.org
Toxicities have limited the use of allogeneic hematopoietic cell transplantation (HCT) to
younger, medically fit patients. In a canine HCT model, a combination of postgrafting …
younger, medically fit patients. In a canine HCT model, a combination of postgrafting …
Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity.
IG Schmidt-Wolf, RS Negrin, HP Kiem… - The Journal of …, 1991 - rupress.org
… at -20C for at least 20 h. Sections were stained either with … intravenously into SCID mice
3-48 h after irradiation. 10 U/ml … into two equal doses and injected 24 h apart. Animals were …
3-48 h after irradiation. 10 U/ml … into two equal doses and injected 24 h apart. Animals were …
Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after …
…, HP Kiem, W Leisenring, H Shulman - Blood, The Journal …, 1997 - ashpublications.org
Postgrafting cyclosporine (CSP) given for 35 days resulted in establishment of stable marrow
grafts from DLA-identical canine littermates after otherwise suboptimal, but nevertheless, …
grafts from DLA-identical canine littermates after otherwise suboptimal, but nevertheless, …
Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus …
…, PA Carpenter, SJ Lee, HP Kiem… - Blood, The Journal …, 2011 - ashpublications.org
Risk factors for grades 2-4 acute graft-versus-host disease (GVHD) and for chronic GVHD as
defined by National Institutes of Health consensus criteria were evaluated and compared in …
defined by National Institutes of Health consensus criteria were evaluated and compared in …
Chimeric antigen receptor T-cell approaches to HIV cure
…, CW Peterson, HP Kiem - Current Opinion in HIV and …, 2018 - journals.lww.com
Despite promising results in preclinical studies, only a handful of clinical trials have been
initiated worldwide. Several obstacles remain prior to successful application of HIV-specific …
initiated worldwide. Several obstacles remain prior to successful application of HIV-specific …
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
The small number of hematopoietic stem and progenitor cells in cord blood units limits their
widespread use in human transplant protocols. We identified a family of chemically related …
widespread use in human transplant protocols. We identified a family of chemically related …