Multiple sclerosis (MS) has long been regarded as a chronic inflammatory disease of the
white matter that leads to demyelination and eventually to neurodegeneration. In the past …

… They were randomly assigned to standard cages, with four to five animals per cage, and
kept at standard housing conditions with a light/dark cycle of 12 h and free access to food and …

… For lymphocytes, before loading into the ELISA plate, equal volumes (1.35 ml) of both 1 h
and 24 h lymphocyte medium were defrosted and concentrated through centrifugal filters with …

Non-targeted screening with LC/HRMS is a go-to approach to discover relevant contaminants
in environmental water samples that contain an abundance of chemicals. The rapidly …

… Mice were housed under constant conditions in an animal facility with a regular 12 h light/dark
cycle. Food and water were supplied ad libitum. All the efforts were made to minimize the …

Nontarget analysis by liquid chromatography–high-resolution mass spectrometry (LC-HRMS)
is now widely used to detect pollutants in the environment. Shifting away from targeted …

Background and Purpose Glutamate transmission is dysregulated in both multiple sclerosis
( MS ) and experimental autoimmune encephalomyelitis ( EAE ), the animal model of MS . A …

Transient receptor potential vanilloid 1 (TRPV1) channels are involved in several inflammatory
diseases. However, their action is still controversial, and both pro-inflammatory and anti-…

… Italy) were randomly assigned to standard cages (4–5 animals per cage) and kept at standard
housing conditions, including a Techniplast Mouse House®, with a light/dark cycle of 12 h …

… Animals were randomly assigned to standard cages, with four to five animals per cage,
and kept at standard housing conditions with a light/dark cycle of 12 h and free access to food …