We review and synthesize recent neurophysiological studies of decision making in humans
and nonhuman primates. From these studies, the basic outline of the neurobiological …

Mice with altered α 2 -adrenergic receptor genes have become important tools in elucidating
the subtype-specific functions of the three α 2 -adrenergic receptor subtypes because of the …

… Drs Lempert, Pinto, and Kable reported no biomedical financial interests or potential conflicts
of interest. Drs Steinglass and Simpson are supported in part by the New York State Office …

Neuroimaging studies of decision-making have generally related neural activity to objective
measures (such as reward magnitude, probability or delay), despite choice preferences …

Numerous experiments have recently sought to identify neural signals associated with the
subjective value (SV) of choice alternatives. Theoretically, SV assessment is an intermediate …

Why does performing certain tasks cause the aversive experience of mental effort and
concomitant deterioration in task performance? One explanation posits a physical resource that is …

Data analysis workflows in many scientific domains have become increasingly complex and
flexible. Here we assess the effect of this flexibility on the results of functional magnetic …

Human concepts can be roughly divided into entities (prototypically referred to in language
by nouns) and events (prototypically referred to in language by verbs). While much work in …

… Four of these 22 had previously participated in a similar experiment in our laboratory (Kable
and Glimcher 2007). Ten participants (3 women, 7 men; mean age = 22.4 yr) with the …

Recent work in neuroeconomics has shown that regions in orbitofrontal and medial prefrontal
cortex encode the subjective value of different options during choice. However, these …