User profiles for J. Besharse
Joseph C BesharseProfessor Emeritus, Medical College of Wisconsin Verified email at mcw.edu Cited by 11614 |
Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors
C Insinna, JC Besharse - … an official publication of the American …, 2008 - Wiley Online Library
… 4) have an average longitudinal spacing of approximately 32 nm (Besharse et al.,1985),
suggesting that they are both part of the same structure. The cytosolic space in the transition …
suggesting that they are both part of the same structure. The cytosolic space in the transition …
Circadian rhythmicity in vertebrate retinas: regulation by a photoreceptor oscillator
GM Cahill, JC Besharse - Progress in retinal and eye research, 1995 - Elsevier
Circadian regulation of retinal function has now been shown in all classes of vertebrates and
attempts are now under way to understand the mechanisms underlying this regulation. The …
attempts are now under way to understand the mechanisms underlying this regulation. The …
Retinal circadian clocks and control of retinal physiology
CB Green, JC Besharse - Journal of biological rhythms, 2004 - journals.sagepub.com
Retinas of all classes of vertebrates contain endogenous circadian clocks that control many
aspects of retinal physiology, including retinal sensitivity to light, neurohormone synthesis, …
aspects of retinal physiology, including retinal sensitivity to light, neurohormone synthesis, …
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance
…, JL Rosenbaum, GB Witman, JC Besharse - The Journal of cell …, 2002 - rupress.org
Approximately 10% of the photoreceptor outer segment (OS) is turned over each day, requiring
large amounts of lipid and protein to be moved from the inner segment to the OS. Defects …
large amounts of lipid and protein to be moved from the inner segment to the OS. Defects …
Circadian clock functions localized in Xenopus retinal photoreceptors
GM Cahill, JC Besharse - Neuron, 1993 - cell.com
A circadian oscillator that regulates visual function is located somewhere within the vertebrate
eye. To determine whether circadian rhythmicity is generated by retinal photoreceptors, …
eye. To determine whether circadian rhythmicity is generated by retinal photoreceptors, …
Circadian clock in Xenopus eye controlling retinal serotonin N-acetyltransferase
JC Besharse, PM Iuvone - Nature, 1983 - nature.com
Circadian rhythms are controlled by endogenous oscillators or clocks. These clocks exhibit a
persistent period of approximately 24 h in constant conditions, a specific phase relationship …
persistent period of approximately 24 h in constant conditions, a specific phase relationship …
Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity
…, D Lourim, SR Keller, JC Besharse - Proceedings of the …, 2007 - National Acad Sciences
The mammalian circadian system consists of a central oscillator in the suprachiasmatic nucleus
of the hypothalamus, which coordinates peripheral clocks in organs throughout the body…
of the hypothalamus, which coordinates peripheral clocks in organs throughout the body…
Turnover of rod photoreceptor outer segments. II. Membrane addition and loss in relationship to light.
JC Besharse, JG Hollyfield, ME Rayborn - The Journal of cell biology, 1977 - rupress.org
… Besharse's present address is the Department of Anatomy, School of Medicine, Emory …
BESHARSE, HOLLYFIELD, AND RAYBORN Membrane Turnover in Rod Outer Segments. …
BESHARSE, HOLLYFIELD, AND RAYBORN Membrane Turnover in Rod Outer Segments. …
Methoxyindoles and photoreceptor metabolism: activation of rod shedding
JC Besharse, DA Dunis - Science, 1983 - science.org
Using an in vitro eye-cup preparation, we have evaluated a potential relationship between
methoxyindole metabolism and photoreceptor disk shedding. Melatonin, 6-chloromelatonin, …
methoxyindole metabolism and photoreceptor disk shedding. Melatonin, 6-chloromelatonin, …
Vesicular transport of newly synthesized opsin from the Golgi apparatus toward the rod outer segment. Ultrastructural immunocytochemical and autoradiographic …
…, BG Schneider, JC Besharse - … & visual science, 1985 - iovs.arvojournals.org
… Postmetamorphic juveniles (3.5 cm long) received a mixture of tritiated amino acids consisting
of 100 j*Ci of L-[(N)-4,5-3H] leucine (specific activity, 50 Ci/mmol) from ICN Chemical and …
of 100 j*Ci of L-[(N)-4,5-3H] leucine (specific activity, 50 Ci/mmol) from ICN Chemical and …